AUTHOR=Zaccardelli Alessandra , Lucas Fabienne M. , LaCasce Ann S. , Chandraker Anil K. , Azzi Jamil R. , Talbot Simon G. TITLE=Case Report: Post-transplant lymphoproliferative disorder as a serious complication of vascularized composite allotransplantation JOURNAL=Frontiers in Transplantation VOLUME=3 YEAR=2024 URL=https://www.frontiersin.org/journals/transplantation/articles/10.3389/frtra.2024.1339898 DOI=10.3389/frtra.2024.1339898 ISSN=2813-2440 ABSTRACT=

Vascularized composite allotransplantation (VCA) is an emerging field in transplant surgery. Despite overall positive outcomes, VCA confers risk for multiple complications related to the procedure and subsequent immunosuppression. Post-transplant lymphoproliferative disorder (PTLD) is a heterogeneous group of lymphoproliferative disorders occurring after solid organ and hematopoietic stem cell transplant. A patient with PTLD after bilateral upper extremity transplantation is presented as well as a review of all known cases of PTLD after VCA, with a focus on the unique epidemiology, presentation, and treatment in this population.