Original Research

Published on 15 Jul 2024

Many human pharmaceuticals are weak inhibitors of the cytochrome P450 system in rainbow trout (Oncorhynchus mykiss) liver S9 fractions

in Environmental Toxicology

Tea Pihlaja
Timo Oksanen
Netta Vinkvist
Tiina Sikanen

Frontiers in Toxicology

doi 10.3389/ftox.2024.1406942

1,020 views
1 citation

Methods

Published on 15 Jul 2024

sendigR: an R package to leverage the value of CDISC SEND datasets for cross-study analysis

in Computational Toxicology and Informatics

K. Snyder
C. M. Sabbir Ahmed
Md Yousuf Ali
S. Butler
Michael DeNieu
W. Houser
B. Paisley
M. Rosentreter
W. Wang
B. Larsen

Frontiers in Toxicology

doi 10.3389/ftox.2024.1392686

1,091 views
1 citation

Original Research

Published on 10 Jul 2024

Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

in Immunotoxicology

Lorena Ndreu
Josefine Carlsson
David J. Ponting
Ida B. Niklasson
E. Johanna L. Stéen
Lukas McHugh
Niamh M. O’Boyle
Kristina Luthman
Ann-Therese Karlberg
Isabella Karlsson

Frontiers in Toxicology

doi 10.3389/ftox.2024.1398852

2,777 views

Editorial

Published on 02 Jul 2024

Editorial: Next generation chemical risk assessment: integration of advances in toxicology, biology and computation

in Computational Toxicology and Informatics

Kan Shao
Chao Ji
Bernard Gadagbui

Frontiers in Toxicology

doi 10.3389/ftox.2024.1440229

643 views

Original Research

Published on 01 Jul 2024

Evaluation of the immunotoxicity potential of nanomaterials using THP-1 cells

in Nanotoxicology

Asuka Nishida
Yuka Sawada
Rion Arai
Naoki Ishibashi
Miho Suzuo
Akiko Ohno
Takao Ashikaga
Kazutoshi Iijima

Frontiers in Toxicology

doi 10.3389/ftox.2024.1293147

911 views
2 citations

Original Research

Published on 13 Jun 2024

Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

in In Vitro Toxicology

Fiona Chapman
Luuk de Haan
Linda Gijzen
Wouter Strijker
Edgar Trelles Sticken
Sarah Jean Pour
Roman Wieczorek
Florian Haberstroh
Sandra Otte
Thomas Nahde

Frontiers in Toxicology

doi 10.3389/ftox.2024.1395670

2,162 views

Review

Published on 13 Jun 2024

Applying new approach methodologies to assess next-generation tobacco and nicotine products

in In Vitro Toxicology

David Thorne
Damian McHugh
Liam Simms
K. Monica Lee
Hitoshi Fujimoto
Sara Moses
Marianna Gaca

Frontiers in Toxicology

doi 10.3389/ftox.2024.1376118

2,659 views

Policy and Practice Reviews

Published on 12 Jun 2024

Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay

in Regulatory Toxicology

Amber Goetz
Natalia Ryan
Alaina Sauve-Ciencewicki
Caleb C. Lord
Gina M. Hilton
Douglas C. Wolf

Frontiers in Toxicology

doi 10.3389/ftox.2024.1394361

1,694 views

Editorial

Published on 07 Jun 2024

Editorial: Linking environmental exposure to toxicants and chronic disease

in Developmental and Reproductive Toxicology

David R. Wallace
Aleksandra Buha Đorđević

Frontiers in Toxicology

doi 10.3389/ftox.2024.1430316

735 views

Original Research

Published on 05 Jun 2024

Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis

in Environmental Toxicology

Archana Hari
Mohamed Diwan M. AbdulHameed
Michele R. Balik-Meisner
Deepak Mav
Dhiral P. Phadke
Elizabeth H. Scholl
Ruchir R. Shah
Warren Casey
Scott S. Auerbach
Anders Wallqvist

Frontiers in Toxicology

doi 10.3389/ftox.2024.1390196

2,239 views
1 citation

Systematic Review

Published on 30 May 2024

Does pyrethroid exposure lower human semen quality? a systematic review and meta-analysis

in Developmental and Reproductive Toxicology

Roland Eghoghosoa Akhigbe
Precious Adeoye Oyedokun
Tunmise Maryanne Akhigbe
Suliat Adenike
Ayoola Abimbola Oladipo
Jennifer Rose Hughes

Frontiers in Toxicology

doi 10.3389/ftox.2024.1395010

1,123 views
1 citation

Review

Published on 30 May 2024

Global challenges in aging: insights from comparative biology and one health

in Environmental Toxicology

Mary Ann Ottinger
Jacquelyn K. Grace
Terri J. Maness

Frontiers in Toxicology

doi 10.3389/ftox.2024.1381178

1,237 views

Perspective

Published on 28 May 2024

The DaNa projects: public communication of (nano)material safety data—from conspiracy theories to study quality

in Nanotoxicology

Dana Kühnel
Harald F. Krug
Christoph Steinbach
Katja Nau

Frontiers in Toxicology

doi 10.3389/ftox.2024.1382458

860 views

Perspective

Published on 23 May 2024

ICH S1 prospective evaluation study and weight of evidence assessments: commentary from industry representatives

in Regulatory Toxicology

John L. Vahle
Joe Dybowski
Michael Graziano
Shigeru Hisada
Jose Lebron
Thomas Nolte
Ronald Steigerwalt
Kenjiro Tsubota
Frank D. Sistare

Frontiers in Toxicology

doi 10.3389/ftox.2024.1377990

1,802 views
1 citation

Original Research

Published on 16 May 2024

Dechloranes and chlorinated paraffins in sediments and biota of two subarctic lakes

in Environmental Toxicology

Aline Arriola
Insam Al Saify
Nicholas A. Warner
Dorte Herzke
Mikael Harju
Per-Arne Amundsen
Anita Evenset
Claudia Möckel
Ingjerd S. Krogseth

Frontiers in Toxicology

doi 10.3389/ftox.2024.1298231

957 views

Original Research

Published on 10 May 2024

The application of natural language processing for the extraction of mechanistic information in toxicology

in Computational Toxicology and Informatics

Marie Corradi
Thomas Luechtefeld
Alyanne M. de Haan
Raymond Pieters
Jonathan H. Freedman
Tamara Vanhaecke
Mathieu Vinken
Marc Teunis

Frontiers in Toxicology

doi 10.3389/ftox.2024.1393662

4,944 views
1 citation

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Articles

Many human pharmaceuticals are weak inhibitors of the cytochrome P450 system in rainbow trout (Oncorhynchus mykiss) liver S9 fractions

sendigR: an R package to leverage the value of CDISC SEND datasets for cross-study analysis

Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

Editorial: Next generation chemical risk assessment: integration of advances in toxicology, biology and computation

Evaluation of the immunotoxicity potential of nanomaterials using THP-1 cells

Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

Applying new approach methodologies to assess next-generation tobacco and nicotine products

Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay

Editorial: Linking environmental exposure to toxicants and chronic disease

Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis

Does pyrethroid exposure lower human semen quality? a systematic review and meta-analysis

Global challenges in aging: insights from comparative biology and one health

The DaNa projects: public communication of (nano)material safety data—from conspiracy theories to study quality

ICH S1 prospective evaluation study and weight of evidence assessments: commentary from industry representatives

Dechloranes and chlorinated paraffins in sediments and biota of two subarctic lakes

The application of natural language processing for the extraction of mechanistic information in toxicology