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PERSPECTIVE article
Front. Toxicol.
Sec. Nanotoxicology
Volume 6 - 2024 |
doi: 10.3389/ftox.2024.1470439
Twenty years of in vitro nanotoxicology: how AI could make the difference
Provisionally accepted- University of Rome Tor Vergata, Roma, Italy
More than two decades ago, the advent of Nanotechnology has marked the onset of a new and critical field in science and technology, highlighting the importance of multidisciplinary approaches to assess and model the potential human hazard of newly developed advanced materials in the nanoscale, the nanomaterials (NMs).Nanotechnology is, by definition, a multidisciplinary field, that integrates knowledge and techniques from physics, chemistry, biology, materials science, and engineering to manipulate matter at the nanoscale, defined as anything comprised between 1 and 100 nanometres. The emergence of nanotechnology has undoubtedly led to significant innovations in many fields, from medical diagnostics and targeted drug delivery systems to advanced materials and energy solutions. However, the unique properties of nanomaterials, such as the increased surface to volume ratio, which provides increased reactivity and hence the ability to penetrate biological barriers, have been also considered as potential risk factors for unforeseen toxicological effects, stimulating the scientific community to investigate to which extent this new field of applications could pose a risk to human health and the environment.
Keywords: In vitro nantoxicology, artificial intelligence, In vitro Models, machine learning, Engineered Nanomaterials (ENM)
Received: 25 Jul 2024; Accepted: 30 Aug 2024.
Copyright: © 2024 Campagnolo, Lacconi, Filippi and Martinelli. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Luisa Campagnolo, University of Rome Tor Vergata, Roma, Italy
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