Frontiers in Toxicology

Original Research

Accepted on 21 Mar 2025

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation

in Computational Toxicology and Informatics

Shigeaki Ito
Sakuya Ichikawa
Risa Matsumoto
Shugo Muratani
Keigo Sano
Akina Mori
Kazuo Erami

Frontiers in Toxicology

doi 10.3389/ftox.2025.1564864

Original Research

Accepted on 21 Mar 2025

Mitigating Heavy Metal Toxicity: The Protective Impact of Sprouted Wheat and

in Food and Nutritional Toxicology

Lamiaa M. Abd El-Maoula
Amira M. Elmoslemany
Hanan S.E. Eldamaty
Amina Zedan
Heba Ghamry
Heba Yahia Elbasiouny
Ola Ibrahim El-Desoky

Frontiers in Toxicology

doi 10.3389/ftox.2025.1537092

Original Research

Published on 21 Mar 2025

Toxic effects of Lepidium sativum seed fixed oil on Wistar albino rats in acute and subacute toxicity models

in Food and Nutritional Toxicology

Teshome Gebremeskel Aragie
Kaleab Asres
Wondwossen Ergete
Samual Woldekidan
Sileshi Degu
Abiy Abebe
Worku Gemechu
Derso Furgasa
Girma Seyoum

Frontiers in Toxicology

doi 10.3389/ftox.2025.1535597

135 views

Original Research

Accepted on 19 Mar 2025

Promising protective potential of MiR-103a-3p against polystyrene microplastic neurotoxicity in rats

in Neurotoxicology

Tourandokht Baluchnejadmojarad
Leila Mohammadi
Mina Goudarzi
Vahid Khodashenas
Roya Khoshravesh
Mehrdad Roghani

Frontiers in Toxicology

doi 10.3389/ftox.2025.1560980

Original Research

Published on 17 Mar 2025

Modeling marine microplastic emissions in Life Cycle Assessment: characterization factors for biodegradable polymers and their application in a textile case study

in Environmental Toxicology

Felicitas Pellengahr
Elena Corella-Puertas
Valérie Mattelin
Nadim Saadi
Francesca Bertella
Anne-Marie Boulay
Yvonne van der Meer

Frontiers in Toxicology

doi 10.3389/ftox.2025.1494220

801 views

Editorial

Published on 17 Mar 2025

Editorial: Global excellence in toxicology: Asia, Australia and New Zealand

in Nanotoxicology

Yongning Wu

Frontiers in Toxicology

doi 10.3389/ftox.2025.1584009

167 views

Review

Accepted on 14 Mar 2025

Acute cannabis intoxication among the paediatric

in Clinical Toxicology

Ginevra Malta
Giuseppe Davide Albano
Gianluca Lavanco
Anna Brancato
Carla Cannizzaro
Antonina Argo
Simona Contorno
Fulvio Plescia
Stefania Zerbo

Frontiers in Toxicology

doi 10.3389/ftox.2025.1558721

Brief Research Report

Accepted on 14 Mar 2025

Elucidating Mechanistic Relationships between Peroxisome Proliferator-activated Receptors and Hepatic Fibrosis using the ROBOKOP Knowledge Graph

in Computational Toxicology and Informatics

Karamarie Fecho
Nyssa Tucker
Jon-Michael Beasley
Scott Auerbach
Chris Bizon
Alexander Tropsha

Frontiers in Toxicology

doi 10.3389/ftox.2025.1549268

Original Research

Published on 14 Mar 2025

Selection of the critical effect size alters hazard characterization – a retrospective analysis of key studies used for risk assessments of PFAS

in Regulatory Toxicology

L. Brunken
A. Vieira Silva
M. Öberg

Frontiers in Toxicology

doi 10.3389/ftox.2025.1525089

378 views

Original Research

Accepted on 13 Mar 2025

Advancing Humanized 3D Tumor Modeling Using an Open Access Xeno-Free Medium

in In Vitro Toxicology

Atena Malakpour-Permlid
Manuel Marcos Rodriguez
Kinga Zór
Anja Boisen
Stina Oredsson

Frontiers in Toxicology

doi 10.3389/ftox.2025.1529360

Review

Published on 13 Mar 2025

Implications of petrochemical exposure and epigenetic alterations on human health

in Environmental Toxicology

Selvaraj Jayaraman
Anupriya Eswaran
Vishnu Priya Veeraraghavan
Mohammed Fazal
Adham Al-Rahbi
Srinivasa Rao Sirasanagandla

Frontiers in Toxicology

doi 10.3389/ftox.2025.1542871

301 views

Perspective

Published on 13 Mar 2025

Pesticides and public health: discussing risks in Brazilian agro-industrial growth

in Developmental and Reproductive Toxicology

Juliana E. Perobelli

Frontiers in Toxicology

doi 10.3389/ftox.2025.1442801

271 views

Original Research

Accepted on 11 Mar 2025

Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus)

in Environmental Toxicology

Bingbu Li
Guixing Wang
Xinyu Zheng
Mingyang Liu
Yucong Yang
Yuqin Ren
Yitong Zhang
Yufeng Liu
Zhongwei He
Jangong Ren

Frontiers in Toxicology

doi 10.3389/ftox.2025.1560192

Editorial

Published on 11 Mar 2025

Editorial: Chemical contaminants in natural environments and human health implications

in Environmental Toxicology

Aina Olubukola Adeogun
Azubuike Victor Chukwuka
Beatrice Olutoyin Opeolu
Oju Ibor
Ebenezer Olatunde Farombi

Frontiers in Toxicology

doi 10.3389/ftox.2025.1528372

264 views

Original Research

Published on 06 Mar 2025

Suppression of the T-dependent antibody response following oral exposure to selected polycyclic aromatic compounds in B6C3F1/N mice

in Immunotoxicology

Victor J. Johnson
Cynthia V. Rider
Michael I. Luster
Cynthia J. Willson
Shawn Harris
Billie Stiffler
James Blake
Esra Mutlu
Veronica Godfrey
Brian Burback

Frontiers in Toxicology

doi 10.3389/ftox.2025.1558639

226 views

Case Report

Published on 27 Feb 2025

Case report: Pesticide-related methemoglobinemia: Tebufenozide and indoxacarb poisoning

in Clinical Toxicology

Jieru Wang
Guangcai Yu
Tianzi Jian
Baotian Kan
Wei Li
Xiangdong Jian

Frontiers in Toxicology

doi 10.3389/ftox.2025.1557990

280 views

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Articles

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation

Mitigating Heavy Metal Toxicity: The Protective Impact of Sprouted Wheat and

Toxic effects of Lepidium sativum seed fixed oil on Wistar albino rats in acute and subacute toxicity models

Promising protective potential of MiR-103a-3p against polystyrene microplastic neurotoxicity in rats

Modeling marine microplastic emissions in Life Cycle Assessment: characterization factors for biodegradable polymers and their application in a textile case study

Editorial: Global excellence in toxicology: Asia, Australia and New Zealand

Acute cannabis intoxication among the paediatric

Elucidating Mechanistic Relationships between Peroxisome Proliferator-activated Receptors and Hepatic Fibrosis using the ROBOKOP Knowledge Graph

Selection of the critical effect size alters hazard characterization – a retrospective analysis of key studies used for risk assessments of PFAS

Advancing Humanized 3D Tumor Modeling Using an Open Access Xeno-Free Medium

Implications of petrochemical exposure and epigenetic alterations on human health

Pesticides and public health: discussing risks in Brazilian agro-industrial growth

Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus)

Editorial: Chemical contaminants in natural environments and human health implications

Suppression of the T-dependent antibody response following oral exposure to selected polycyclic aromatic compounds in B6C3F1/N mice

Case report: Pesticide-related methemoglobinemia: Tebufenozide and indoxacarb poisoning