AUTHOR=Takeda Yuto , Hata Katsuhiko , Yamazaki Tokio , Kaneko Masaki , Yokoi Osamu , Tsai Chengta , Umemura Kazuo , Nikuni Tetsuro TITLE=Numerical Simulation: Fluctuation in Background Synaptic Activity Regulates Synaptic Plasticity JOURNAL=Frontiers in Systems Neuroscience VOLUME=15 YEAR=2021 URL=https://www.frontiersin.org/journals/systems-neuroscience/articles/10.3389/fnsys.2021.771661 DOI=10.3389/fnsys.2021.771661 ISSN=1662-5137 ABSTRACT=
Synaptic plasticity is vital for learning and memory in the brain. It consists of long-term potentiation (LTP) and long-term depression (LTD). Spike frequency is one of the major components of synaptic plasticity in the brain, a noisy environment. Recently, we mathematically analyzed the frequency-dependent synaptic plasticity (FDP)