AUTHOR=Hawkes Richard 

TITLE=Purkinje cell stripes and long-term depression at the parallel fiber-Purkinje cell synapse

JOURNAL=Frontiers in Systems Neuroscience

VOLUME=8

YEAR=2014

URL=https://www.frontiersin.org/journals/systems-neuroscience/articles/10.3389/fnsys.2014.00041

DOI=10.3389/fnsys.2014.00041

ISSN=1662-5137

ABSTRACT=<p>The cerebellar cortex comprises a stereotyped array of transverse zones and parasagittal stripes, built around multiple Purkinje cell subtypes, which is highly conserved across birds and mammals. This architecture is revealed in the restricted expression patterns of numerous molecules, in the terminal fields of the afferent projections, in the distribution of interneurons, and in the functional organization. This review provides an overview of cerebellar architecture with an emphasis on attempts to relate molecular architecture to the expression of long-term depression (LTD) at the parallel fiber-Purkinje cell (pf-PC) synapse.</p>