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ORIGINAL RESEARCH article
Front. Surg.
Sec. Thoracic Surgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1553699
Observational study of the recent efficacy and economy of itraconazole versus voriconazole in perioperative pulmonary aspergillosis
Provisionally accepted
Peng Chen 1,2
Xiao Zhang 1,2
Xinzhe Zheng 1,2
Yang Tang 1,2
Yongxiang Song 1,2
Xixian Ke 1,2
Cheng Chen 1,2*- 1 Affiliated Hospital of Zunyi Medical University, Zunyi, China
- 2 Department of Thoracic Surgery, Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou Province, China
Background: Antifungal therapy is a common treatment option for pulmonary aspergillosis, but its use to prevent recurrence and relieve symptoms in patients with pulmonary aspergillosis remains controversial. This study aimed to explore the short-term efficacy and cost of itraconazole versus voriconazole in the treatment of pulmonary aspergillosis during the perioperative period. Methods:We retrospectively collected the clinical data of 55 patients with pulmonary aspergillosis who underwent surgery and received itraconazole or voriconazole as antifungal therapy between January
Keywords: Itraconazole, Voriconazole, antifungal therapy, Pulmonary Aspergillosis, Perioperative
Received: 31 Dec 2024; Accepted: 19 Mar 2025.
Copyright: © 2025 Chen, Zhang, Zheng, Tang, Song, Ke and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Cheng Chen, Affiliated Hospital of Zunyi Medical University, Zunyi, China
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