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CASE REPORT article

Front. Surg.
Sec. Orthopedic Surgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1472886

Case Report: Intradural Gout Tophi without Systemic Gout Symptom

Provisionally accepted
Peidong Qing Peidong Qing 1Shiming Xie Shiming Xie 1Chaoqun Feng Chaoqun Feng 2Hongda Xu Hongda Xu 1Shengxin Zhao Shengxin Zhao 1Lei Zhang Lei Zhang 1Haitao Deng Haitao Deng 1Ye-Hui Wang Ye-Hui Wang 3Youpeng Hu Youpeng Hu 1*
  • 1 Mianyang Orthopedic Hospital, Mianyang, China
  • 2 Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China
  • 3 Sichuan Provincial Orthopedics Hospital, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

    Background: Gout is a common disease; however, gout tophus occurring within the spinal dura is exceedingly rare, with only two cases reported to date.We report the case of a 70-year-old female who presented with lower back pain, right radicular pain, and numbness in the perineal area. Magnetic resonance imaging and computed tomography scans revealed a calcified intradural lesion at the L3 level. The diagnosis of the lesion was not definitive because the patient had no history of gout or manifestations of systemic gout. Surgical removal of the intradural lesion followed by pathological examination confirmed gouty tophi.The postoperative recovery was good, and the patient experienced substantial relief from pain and numbness.This is the third documented case of gout tophi occurring within the spinal dura. According to the literature review, it was found that none of these three patients with intradural gouty tophus had systemic gout manifestations or hyperuricemia, which is a very crucial finding. As it is challenging to diagnose intradural gout, awareness among physicians must be increased to optimize the treatment and outcomes for these patients.

    Keywords: Gout tophi, Spinal dura, Intradural gout, Hyperuricemia, lumbar scoliosis, neurological damage

    Received: 30 Jul 2024; Accepted: 10 Jan 2025.

    Copyright: © 2025 Qing, Xie, Feng, Xu, Zhao, Zhang, Deng, Wang and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Youpeng Hu, Mianyang Orthopedic Hospital, Mianyang, 621000, China

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