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ORIGINAL RESEARCH article

Front. Surg.
Sec. Neurosurgery
Volume 12 - 2025 | doi: 10.3389/fsurg.2025.1438307
This article is part of the Research Topic Immune Therapies in Neurological Disorders View all 3 articles

Comparative Clinical Impact of Low-Curvature and Normal-Curvature Titanium Mesh in Cranioplasty: A Retrospective Analysis of Patient Outcomes

Provisionally accepted
Shengkai Yang Shengkai Yang Weihua Chen Weihua Chen Hongwei Teng Hongwei Teng Lei Zhang Lei Zhang Kangkang Ji Kangkang Ji Hai Zhou Hai Zhou *
  • Binhai County People's Hospital, Yancheng, China

The final, formatted version of the article will be published soon.

    Objective This study aimed to evaluate the clinical utility of two types of cranioplasty surgery involving low-curvature and normal-curvature titanium mesh, respectively.Methods The clinical data were retrospectively collected from patients undergoing skull defect repair surgery between January 2021 and December 2022. The clinical outcomes associated with the two surgical approaches were compared and analyzed.Results A total of 67 patients who underwent skull defect repair surgery were enrolled, with 22 in the low-curvature titanium mesh group and 45 in the normal-curvature titanium mesh group. Both before and after propensity score matching (PSM) analysis, the hospital stay for the low-curvature titanium mesh group was significantly shorter than that for the normal-curvature mesh group (Before: 9.14±2.64 vs. 12.51±4.15, P = 0.001; After: 9.44±2.83 vs. 12.13±4.40, P = 0.048). The low-curvature group exhibited lower overall hospitalization costs than the normal-curvature group (Before: 23500. ± 900. vs. 24900. ± 1100., P < 0.001; After: 23300. ± 800. vs. 24100. ± 1000., P = 0.026). Moreover, satisfaction with molding (Before: 4.23±0.75 vs. 3.18±0.81, P = 0.001; After: 4.13±0.72 vs. 3.25±0.78, P < 0.001), Karnofsky’s Performance Status score (Before: 93.32±1.67 vs. 90.38±3.50, P = 0.001; After: 93.56±1.75 vs. 91.00±3.78, P < 0.001), and Quality of Life score (Before: 52.95±2.13 vs. 50.18±3.54, P = 0.001; After: 53.31±2.12 vs. 50.38±4.23, P = 0.001) were significantly higher in the low-curvature titanium mesh group than the normal-curvature titanium mesh group.Conclusions Applying low-curvature titanium mesh for skull repair effectively shortens the hospital stay, reduces overall hospitalization costs, enhances patient satisfaction with surgical modeling, and improves the postoperative functional status and quality of life of patients undergoing neurosurgery. These advantages warrant further clinical promotion.

    Keywords: Hypertensive intracerebral hemorrhages, Low-curvature titanium mesh, Normal-curvature titanium mesh, cranioplasty, PSM

    Received: 30 May 2024; Accepted: 24 Jan 2025.

    Copyright: © 2025 Yang, Chen, Teng, Zhang, Ji and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Hai Zhou, Binhai County People's Hospital, Yancheng, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.