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ORIGINAL RESEARCH article

Front. Surg.
Sec. Genitourinary Surgery
Volume 11 - 2024 | doi: 10.3389/fsurg.2024.1475030

Mid-urethral sling with proper sling tension is an effective treatment for stress urinary incontinence in women after pelvic radiotherapy: A pilot study of case series

Provisionally accepted
Xing Guan Xing Guan 1Fei Wang Fei Wang 1Di Zhang Di Zhang 1Peng Qiao Peng Qiao 1Yan Qin Yan Qin 2Biao Wang Biao Wang 1*
  • 1 Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
  • 2 Urology, Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University, Nanning, China

The final, formatted version of the article will be published soon.

    Background: At present, consensus on the management of female stress urinary incontinence (SUI) after pelvic radiotherapy is lacking. We aim to assess the clinical effects of mid-urethral sling (MUS) for the treatment of SUI after pelvic radiotherapy in women. Methods: We conducted a retrospective review of the clinical database of female with SUI after pelvic radiotherapy from June 2015 to February 2022. The clinical efficacy was evaluated by International Consultation on Incontinence Questionnaire-Short Form (ICI-Q-SF) questionnaire, maximum flow rate (Qmax) and postvoid residual (PVR) urine. All patients were reviewed postoperatively in an outpatient clinic. Results: We identified 26 patients with mean age of 59.35±7.32 years. All the patients who suffered from SUI had a history of gynaecological malignancies and received pelvic radiotherapy. 21 patients (80.77%, 95% CI: 0.621-0.915) were considered to have successfully improved after surgery, the ICI-Q-SF scores were lower than the preoperative at 2 weeks, 6 months and 1 year postoperatively (P＜0.01). After 1-year follow-up, none of the patients had mesh erosion. Conclusion: SUI following radiotherapy for the treatment of pelvic malignancy can be challenging to manage. MUS is a highly effective and safe option for the treatment of SUI after radiotherapy, additionally, that proper sling tension is the key to the success of the procedure.

    Keywords: Stress urinary incontinence, pelvic radiotherapy, Mid-urethral sling, Lower Urinary Tract Symptoms, pelvic tumor Running title: Female stress urinary incontinence after pelvic radiotherapy

    Received: 02 Aug 2024; Accepted: 13 Dec 2024.

    Copyright: © 2024 Guan, Wang, Zhang, Qiao, Qin and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Biao Wang, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.