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BRIEF RESEARCH REPORT article

Front. Surg.
Sec. Visceral Surgery
Volume 11 - 2024 | doi: 10.3389/fsurg.2024.1462885

Early vs. interval approach to laparoscopic cholecystectomy for acute cholecystitis: a retrospective observational study from pakistan

Provisionally accepted
Sandesh Raja Sandesh Raja 1Azzam Ali Azzam Ali 2*Dileep Kumar Dileep Kumar 3Adarsh Raja Adarsh Raja 4Khursheed Ahmed Samo Khursheed Ahmed Samo 3Amjad Siraj Memon Amjad Siraj Memon 5
  • 1 Dow Medical College, Dow University of Health Sciences, Karachi, Punjab, Pakistan
  • 2 Dow University of Health Sciences, Karachi, Pakistan
  • 3 Dr. Ruth K. M. Pfau, Civil Hospital Karachi, Karachi, Punjab, Pakistan
  • 4 Shaheed Mohtarma Benazir Bhutto Medical College, Lyari, Karachi, Pakistan
  • 5 Jinnah Sindh Medical University, Karachi, Sindh, Pakistan

The final, formatted version of the article will be published soon.

    Laparoscopic cholecystectomy (LC) is the preferred treatment for acute cholecystitis (AC). However, the optimal timing for LC in AC management remains uncertain, with early cholecystectomy (EC) and interval cholecystectomy (IC) being two common approaches influenced by various factors.This retrospective study, conducted at a tertiary care teaching hospital in Karachi, Pakistan, aimed to compare the outcomes of EC versus IC for AC management. Patient data from January 2019 to September 2019 were analyzed with a focus on operative complications, duration of surgery, and postoperative hospital stay. The inclusion criteria were based on the Tokyo Guidelines, and patients underwent LC within 3 days of symptom onset in the EC group and after 6 weeks in the IC group.Among 147 eligible patients, 100 underwent LC (50 in each group). No significant differences were observed in the sex distribution or mean age between the two groups. The EC group experienced fewer operative complications (12%) than the IC group (34%), with statistically significant differences observed. Nevertheless, no substantial variations in operative time or postoperative hospital stay were observed between the groups.Reduced complications in the EC group underscore its safety and efficacy. Nonetheless, further validation through multicenter studies is essential to substantiate these findings.

    Keywords: Acute cholecistitis, laparoscopic cholecystectomy, Early cholecystectomy, Interval cholecystectomy, complications

    Received: 10 Jul 2024; Accepted: 23 Aug 2024.

    Copyright: © 2024 Raja, Ali, Kumar, Raja, Samo and Memon. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Azzam Ali, Dow University of Health Sciences, Karachi, Pakistan

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