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CASE REPORT article

Front. Surg.
Sec. Reconstructive and Plastic Surgery
Volume 11 - 2024 | doi: 10.3389/fsurg.2024.1457593

Exacerbation after fat grafting in patients with active localized scleroderma

Provisionally accepted
  • Southern Medical University, Guangzhou, China

The final, formatted version of the article will be published soon.

    Background: The application of autologous fat transplantation in facial lesions of patients with localized scleroderma has been reported in recent years.The authors report a case of worsening of active localized scleroderma after autologous fat transplantation. Methods: A man presented with neck and facial skin atrophy and pigmentation with a history of LS. Appearing 1.5 years ago, the lesion had progressively grown in size and shape. Consent is obtained after the patient is informed of the possible surgical risks during the active phase of the disease. He underwent autologous fat grafting into the right cheek with about 30 ml Coleman fat graft. Results: Skin dyspigmentation and atrophy progressively deteriorated one month into therapy, with slightly increased erythema and enlargement of the lesion. Six months after the therapy, localized scleroderma related score worsened. Limitations: There are different factors such as systemic medications could affect the treatment of localized scleroderma by autologous fat transplantation. Meanwhile, considering the limitation of six-month follow-up period, obtaining long-term follow-up data is necessary to evaluate sustained outcomes and potential complications.Conlusion: More clinical research is needed to determine the time interval between disease inactivity and the application of any surgical procedures to avoid reactivation.

    Keywords: Autologous fat grafting, morphea, Localized scleroderma, Active stage, Pigmentary

    Received: 01 Jul 2024; Accepted: 08 Aug 2024.

    Copyright: © 2024 Han, Liu, Lu and junr. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Caii junr, Southern Medical University, Guangzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.