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ORIGINAL RESEARCH article

Front. Surg.
Sec. Genitourinary Surgery
Volume 11 - 2024 | doi: 10.3389/fsurg.2024.1445808

Allium Covered Metal Stent for Treatment of Malignant Ureteral Obstruction

Provisionally accepted
Jing Qing Jing Qing Ke Hu Ke Hu Xuan Zhang Xuan Zhang Huaming Luo Huaming Luo Jiangchuan Chen Jiangchuan Chen Changlong Li Changlong Li Jiamo Zhang Jiamo Zhang *
  • Department of Urology, Yongchuan Hospital, Chongqing Medical University,, Chongqing, China

The final, formatted version of the article will be published soon.

    Background: Malignant ureteral obstruction (MUO) has the potential to result in a range of outcomes, including varying degrees of hydronephrosis and renal impairment. Allium covered metal stents have provided a new, highly effective treatment option for MUO. Our objective was to evaluate the safety and efficacy of the Allium covered metallic stent for the treatment of malignant ureteral obstruction. Methods: Clinical data of 29 patients who underwent endoscopic insertion of an Allium ureteral stent between October 2019 and August 2021 at Yongchuan Hospital, affiliated with Chongqing Medical University, were analyzed retrospectively. At one, three, six and 12 months after insertion, serum creatinine was measured, the width of the renal pelvis was rechecked under ultrasound guidance, and the position and shape of the stent were checked by abdominal X-ray. Data on long-term stent patency, incidence of complications, changes in renal function and hydronephrosis grade were collected and analyzed. Ureteral stent symptom questionnaire (USSQ) was administered preoperatively and after six months in 22 patients with previous stent history. Results: Allium covered metal stents (n=33) were implanted successfully in 29 patients who were followed for three to 22 months, with 32/33 stents remaining patent. Serum creatinine levels decreased in 17 patients (p<0.001), and hydronephrosis decreased in 24 patients. Clavien-Dindo grade I complications were observed in seven patients, Clavien-Dindo II in one patient, whereas stent displacement and stent encrustation occurred in one patient each (Clavien-Dindo III-IV). USSQ scores had significantly improved six months after stent insertion (p<0.001). Conclusions: Allium ureteral stents are a safe and effective treatment option for malignant ureteral obstruction, with good long-term patency, helping to preserve renal function and improve quality of life.

    Keywords: malignant ureteral obstruction, Allium, Ureteral stenting, Ureteroscopy, Metal stent, Endoscopic treatment

    Received: 08 Jun 2024; Accepted: 01 Nov 2024.

    Copyright: © 2024 Qing, Hu, Zhang, Luo, Chen, Li and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jiamo Zhang, Department of Urology, Yongchuan Hospital, Chongqing Medical University,, Chongqing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.