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ORIGINAL RESEARCH article

Front. Surg.
Sec. Surgical Oncology
Volume 11 - 2024 | doi: 10.3389/fsurg.2024.1371968
This article is part of the Research Topic Comprehensive Treatment Strategy for Improving Surgical Resection Rate of Retroperitoneal Sarcomas View all 5 articles

Clinical Features and Outcomes of Retroperitoneal Unicentric Castleman Disease Resected as Sarcomas: Insights from a High-Volume Sarcoma Center

Provisionally accepted
Haicheng Gao Haicheng Gao *Wenjie Li Wenjie Li Boyuan Zou Boyuan Zou Shibo Liu Shibo Liu Chengli Miao Chengli Miao
  • International Hospital, Peking University, Beijing, China

The final, formatted version of the article will be published soon.

    Background: Castleman disease (CD) is a rare lymphoproliferative disorder that can occur anywhere along the lymphatic pathway. Retroperitoneal unicentric Castleman disease (UCD) is an extremely rare manifestation. This study aims to explore the clinical features and surgical treatment of retroperitoneal UCD. Methods: We retrospectively reviewed patients who underwent retroperitoneal tumor surgery and were diagnosed with CD based on postoperative pathology before December 31, 2022. Data from these patients were collected and analyzed. Results: A total of 15 patients were included in the final analysis. All patients underwent radical resection under general anesthesia. Two out of 15 patients (13.3%) experienced serious complications but recovered well. There were no perioperative deaths. The median follow-up time was 78.5 months (range: 18-107.5 months), and no deaths or recurrences occurred during this period. Conclusions: Surgical treatment for retroperitoneal UCD is safe. Patients with retroperitoneal UCD can achieve long-time survival through complete resection.

    Keywords: Unicentric Castleman disease, Retroperitoneal, Surgery, complications, prognosis

    Received: 17 Jan 2024; Accepted: 27 Aug 2024.

    Copyright: © 2024 Gao, Li, Zou, Liu and Miao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Haicheng Gao, International Hospital, Peking University, Beijing, China

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