AUTHOR=Viel Giovanni , Ciarleglio Francesco A. , Frisini Marco , Marcucci Stefano , Valcanover Stefano , Bragantini Emma , Barbareschi Mattia , Mereu Liliana , Tateo Saverio , Merola Elettra , Armelao Franco , De Pretis Giovanni , Brolese Marco , Decarli Nicola L. , Brolese Alberto 

TITLE=Appendiceal collision tumors: case reports, management and literature review

JOURNAL=Frontiers in Surgery

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2023.1184322

DOI=10.3389/fsurg.2023.1184322

ISSN=2296-875X

ABSTRACT=<p>Appendiceal tumors are incidentally detected in 0.5% cases of appendectomy for acute appendicitis and occur in approximately 1% of all appendectomies. Here, we report two cases of appendiceal collision tumors in two asymptomatic women. In both cases, imaging revealed right-lower-quadrant abdominal masses, which were laparoscopically resected. In both cases, histological examinations revealed an appendiceal collision tumor comprising a low-grade appendiceal mucinous neoplasm and well-differentiated neuroendocrine neoplasm (NEN). For complete oncological control, right hemicolectomy was performed in one patient for the aggressive behavior of NEN; however, histology revealed no metastasis. The other patient only underwent appendectomy. No further treatment was recommended. According to the latest guidelines, exact pathology needs to be defined. Proper management indicated by a multidisciplinary team is fundamental.</p>