AUTHOR=Wang Ziqi , Luo Gan , Yu Hongwei , Zhao Hui , Li Tianhao , Yang Houzhi , Sun Tianwei 

TITLE=Comparison of discover cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical degenerative disc diseases: A meta-analysis of prospective, randomized controlled trials

JOURNAL=Frontiers in Surgery

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2023.1124423

DOI=10.3389/fsurg.2023.1124423

ISSN=2296-875X

ABSTRACT=<sec><title>Objective</title><p>This study aims to evaluate the clinical efficacy and safety between Discover cervical disc arthroplasty (DCDA) and anterior cervical discectomy and fusion (ACDF) in Cervical degenerative disc diseases.</p></sec><sec><title>Methods</title><p>Two researchers independently conducted a search of PubMed, EMBASE, and Cochrane Central Register of Controlled Trails (CENTRAL) for randomized controlled trials (RCTs) following the Cochrane methodology guidelines. A fixed-effects or random-effects model was applied based on different heterogeneity. Review Manager (Version 5.4.1) software was used to perform data analysis.</p></sec><sec><title>Results</title><p>A total of 8 RCT studies were included in this meta-analysis. The results indicate that the DCDA group had a higher incidence of reoperation (<italic>P</italic> = 0.03) and a lower incidence of ASD (<italic>P</italic> = 0.04) than the CDA group. There was no significant difference between two groups regarding NDI score (<italic>P</italic> = 0.36), VAS ARM score (<italic>P</italic> = 0.73), VAS NECK score (<italic>P</italic> = 0.63), EQ-5D score (<italic>P</italic> = 0.61) and dysphagia incidence (0.18).</p></sec><sec><title>Conclusion</title><p>DCDA and ACDF have similar results in terms of NDI scores, VAS scores, EQ-5D scores, and dysphagia. In addition, DCDA can reduce the risk of ASD but increases the risk of reoperation.</p></sec>