AUTHOR=Yu Junye , Yu Lifei , Su Lin , Shi Ying 

TITLE=The Correlation Between Intra-Abdominal Pressure and Tolerance to Postoperative Hyperthermic Intraperitoneal Chemotherapy for Pseudomyxoma Peritonei

JOURNAL=Frontiers in Surgery

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2022.797811

DOI=10.3389/fsurg.2022.797811

ISSN=2296-875X

ABSTRACT=<sec><title>Objective</title><p>To evaluate the correlation between pain intensity and comfort level in patients with pseudomyxoma peritoneum (PMP) before and after hyperthermic intraperitoneal chemotherapy (HIPEC).</p></sec><sec><title>Methods</title><p>From June 2018 to June 2019, patients who underwent HIPEC for PMP after surgical treatment in our institute were selected. The intra-abdominal pressure (IAP) and pain intensity (PI) before and after HIPEC were recorded, and the correlation between them was analyzed.</p></sec><sec><title>Results</title><p>Seventy-four patients received HIPEC 253 times. IAP and PI were significantly higher after perfusion than before perfusion (<italic>P</italic> &lt; 0.05). When IAP &lt; 12 cmH<sub>2</sub>O, the change of PI was not correlated to the increase of IAP, and the patient tolerated the treatment. However, when IAP &gt; 12 cmH<sub>2</sub>O, the increase of PI was significantly associated with IAP and cause significant discomfort during the treatment.</p></sec><sec><title>Conclusion</title><p>IAP may be a monitoring index for the comfort of PMP patients during the postoperative HIPEC treatment.</p></sec>