AUTHOR=Ma Ming , Zhu Feng , Fan Fudong , Pan Jun , Cao Hailong , Zhou Qing , Wang Dongjin 

TITLE=Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection

JOURNAL=Frontiers in Surgery

VOLUME=9

YEAR=2023

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2022.1103290

DOI=10.3389/fsurg.2022.1103290

ISSN=2296-875X

ABSTRACT=<sec><title>Background</title><p>Lymphocyte-to-monocyte ratio (LMR) is associated with the mortality of cardiovascular diseases. However, the relationship between preoperative LMR and the prognosis of patients with Stanford type A aortic dissection (TAAD) undergoing surgical treatment remains to be determined.</p></sec><sec><title>Methods</title><p>We enrolled 879 patients with TAAD undergoing surgical treatment between January 2018 and December 2021. Patients were divided into two groups: the Deceased group and the Survived group. The baseline clinical and operative characteristics of the two groups were compared and analyzed.</p></sec><sec><title>Results</title><p>In univariate and multivariate logistic regression analysis, the association between LMR and in-hospital mortality was significant, and LMR (OR = 1.598, 95% CI 1.114–2.485, <italic>P</italic> = 0.022) remained significant after adjusting for confounders.</p></sec><sec><title>Conclusion</title><p>Lower LMR may be independently associated with higher in-hospital mortality in TAAD undergoing surgical treatment.</p></sec>