AUTHOR=Zhou Jingjing , Cai Ting , Wu Dongwen , Chen Xiong , Wang Fen 

TITLE=The role of endoscopic ultrasound-guided fine-needle aspiration/biopsy in the diagnosis of mediastinal lesions

JOURNAL=Frontiers in Surgery

VOLUME=9

YEAR=2023

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2022.1065070

DOI=10.3389/fsurg.2022.1065070

ISSN=2296-875X

ABSTRACT=<sec><title>Objective</title><p>Endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/FNB) is an accurate technique for sampling the pancreas and mediastinum. The aim of this study was to determine the value of EUS-FNA/FNB in the diagnosis of mediastinal lesions.</p></sec><sec><title>Methods</title><p>Data from 107 patients who underwent EUS-FNA/FNB for mediastinal lesions were evaluated.</p></sec><sec><title>Results</title><p>The sensitivity, specificity, positive predictive value, and negative predictive value of EUS-FNA/FNB for mediastinal lesions were 92.00%, 100%, 100%, and 85%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of EUS-FNA for malignant mediastinal lesions were 92.00%, 100%, 100%, and 86.00%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of EUS-FNB for malignant mediastinal lesions were 92.00%, 100%, 100%, and 82.00%, respectively. Except for the discomfort caused by conventional gastroscopy, none of the patients had any complications, such as damage to surrounding large blood vessels or nerves.</p></sec><sec><title>Conclusion</title><p>EUS-FNA/FNB is an effective tool for diagnosing unknown mediastinal lesions, without any obvious complications.</p></sec>