AUTHOR=Shang Feng , Zhao Hao , Cheng Weitao , Qi Meng , Wang Ning , Qu Xin 

TITLE=Predictive Value of the Serum Albumin Level on Admission in Patients With Spontaneous Subarachnoid Hemorrhage

JOURNAL=Frontiers in Surgery

VOLUME=8

YEAR=2021

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2021.719226

DOI=10.3389/fsurg.2021.719226

ISSN=2296-875X

ABSTRACT=<p><bold>Objective:</bold> To determine the effect of the serum albumin level on admission in patients with spontaneous subarachnoid hemorrhage (SAH).</p><p><bold>Methods:</bold> A total of 229 patients with SAH were divided into control and hypoalbuminemia groups. The serum albumin levels were measured. The data, including age, gender, co-existing medical conditions, risk factors, Hunt-Hess (H-H) grade on admission, Glasgow coma score (GCS) on admission, complications during hospitalizations, length of hospital stay, length of intensive care unit (ICU) stay, in-hospital mortality, survival rate, outcome at discharge, and the 6-month follow-up outcome, were compared between the two groups.</p><p><bold>Results:</bold> Older age, an increased number of patients who consumed an excess of alcohol, and a lower GCS on admission were findings in the hypoalbuminemia group compared to the control group (<italic>p</italic> &lt; 0.001). The ratio of patients with H-H grade I on admission in the hypoalbuminemia group was decreased compared to the control group (<italic>p</italic> &lt; 0.05). Patients with hypoalbuminemia were more likely to be intubated, and have pneumonia and cerebral vasospasm than patients with a normal albumin level on admission (<italic>p</italic> &lt; 0.001). Furthermore, the length of hospital and ICU stays were longer in the hypoalbuminemia group than the control group (<italic>p</italic> &lt; 0.001). Hypoalbuminemia on admission significantly increased poor outcomes at discharge (<italic>p</italic> &lt; 0.001). The number of patients with severe disability was increased and the recovery rate was decreased with respect to in-hospital outcomes in the hypoalbuminemia group than the control group (<italic>p</italic> &lt; 0.001).</p><p><bold>Conclusion:</bold> Hypoalbuminemia was shown to be associated with a poor prognosis in patients with SAH.</p>