AUTHOR=Materazzo Marco , Vanni Gianluca , Pellicciaro Marco , Anemona Lucia , Servadei Francesca , Giacobbi Erika , Farinaccio Andrea , Pistolese Chiara Adriana , Perretta Tommaso , Chiocchi Marcello , Bruno Valentina , Tacconi Federico , Sadri Amir , De Majo Adriano , Di Pasquali Camilla , Meucci Rosaria , Santori Francesca , Cotesta Maria , Buonomo Oreste Claudio TITLE=Case Report: Early Breast Cancer Recurrence Mimicking BIA-ALCL in a Patient With Multiple Breast Procedures JOURNAL=Frontiers in Surgery VOLUME=8 YEAR=2021 URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2021.606864 DOI=10.3389/fsurg.2021.606864 ISSN=2296-875X ABSTRACT=

Breast reconstruction plays a fundamental role in the therapeutic process of breast cancer treatment and breast implants represents the leading breast reconstruction strategy. Breast Implant Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL), locoregional recurrence in the skin flap, and skin flap necrosis are well-known complications following mastectomy and immediate breast reconstruction (IBR). We report a case of locoregional cancer recurrence in the mastectomy flap mimicking BIA-ALCL, in a patient who underwent 6 breast procedures in four facilities across 15 years including immediate breast reconstruction with macrotextured breast implants. Despite the rate and onset of the disease, clinicians should be aware of BIA-ALCL. Due to the risk of false negative results of fine needle aspiration, clinical suspicion of BIA-ALCL should drive clinicians' choices, aside from cytological results. In the present case, surgical capsulectomy of the abnormal periprosthesic tissue revealed locoregional recurrence.