AUTHOR=Mooney Michael A. , Simon Elias D. , Little Andrew S. 

TITLE=Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms

JOURNAL=Frontiers in Surgery

VOLUME=3

YEAR=2016

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2016.00045

DOI=10.3389/fsurg.2016.00045

ISSN=2296-875X

ABSTRACT=<p>The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for patients with excess growth hormone levels. We highlight the use of molecular therapies in this disease process and advances in this field, which may represent a paradigm shift for the future of pituitary adenoma treatment.</p>