Shaoqing Chen
Qing Wang2†
Baoguo Shi- 1Physical Education Teaching and Research Department, Capital Normal University, Beijing, China
- 2Beijing Key Laboratory of Learning and Cognition, School of Psychology, Capital Normal University, Beijing, China
- 3School of Teacher Education, Capital Normal University, Beijing, China
Although previous studies indicated that intrinsic motivation and positive affect were important for creativity and proved the benefits of physical exercise for creativity, little is known about underlying this relationship between self-determination in physical exercise and creative personality among college students. Based on prior studies and theoretical models, the current study investigated the relationship between self-determination in physical exercise and creativity and the moderating role of positive affect in the relationship between self-determination in physical exercise and creative personality. This model was analyzed with 1,201 Chinese college students (Mean age = 20.10 years, SD = 0.93). Participants filled out the physical exercise self-determination scale, the Williams creativity assessment packet, and the satisfaction with life scale. The results indicated that self-determination in physical exercise was significantly positively correlated with the creative personality of college students, including risk-taking, curiosity, challenge, and imagination. Moreover, self-determination in physical exercise could significantly positively predict the creative personality of college students. Moderation analysis further showed that the relationship between self-determination in physical exercise and creative personality was robust for college students with low levels of positive affect. These findings suggest the importance of cultivating students' creative ability through improving exercise autonomy, especially for those college students with a low level of positive affect.
Introduction
Creativity, characterized as the generation of novel and useful ideas by individuals, has been integrated into daily life and links with various domains such as science, art, and sports (Amabile, 1982, 1983; Craft, 2006). Moreover, it is critical for the competition in different nations and the development of individuals (Gan et al., 2020). According to the 4P model of creativity, creativity is defined by the person, product, process, and place; among them, creative personality is an essential component of creativity (Rhodes, 1961; Kozbelt et al., 2010). Creative personality refers to the sum of various psychological qualities of an individual with a tendency for creative activities and is the intrinsic basis of creativity (Kozbelt et al., 2010). Specifically, creative personality includes risk-taking, curiosity, challenge, and imagination (Williams, 1980). There is extensive evidence that creativity is associated with physical exercise (Steinberg et al., 1997; Frith and Loprinzi, 2018; Román et al., 2018; Zhao et al., 2022). Significantly, prior studies indicated that individuals participate in activities out of extrinsic motivation, such as self-improvement, and it is conducive to the increase of creativity (Amabile, 1985; Hennessey and Amabile, 1998; Sansone and Harackiewicz, 2000; Moneta and Siu, 2002; Gerhart and Fang, 2015). By that analogy, individuals' self-determination in physical exercise can also improve their creativity. The dynamic componential model of creativity points out that intrinsic motivation, which is individuals taking part in an activity because it is enjoyable or meaningful, was the necessary ingredient for creativity (Amabile, 1983, 1988; Amabile and Pratt, 2016). Moreover, the positive affect plays a crucial role in the creativity-related process (Amabile and Pratt, 2016). Given the effects of physical exercise, motivation, and emotion on creative personality, it is of theoretical and practical importance to explore those factors related to creative personality.
However, to date, most research only focuses on the independent effects of physical exercise, motivation, and positive emotions on creativity. Few researchers have paid attention to the influence of self-determination in physical exercise on the creative personality and the moderating mechanism of positive affect between self-determination in physical exercise and creative personality. Due to the need for creativity and the potential benefits of physical exercise, it is important to explore the impact of combining physical exercise with autonomous motivation on creative personality and investigate its internal affect moderating mechanism.
Self-determination in Physical Exercise and Creative Personality
Self-determination in physical exercise refers to the subjective feeling of the degree of the intrinsic drive of an individual during physical exercise (Wang et al., 2019). Specifically, self-determination in physical exercise includes a sense of belonging, identification, internal integration, competence in physical exercise, and body confidence (Fang et al., 2012). Individuals with a high level of self-determination in physical exercise are more willing to engage voluntarily and actively (Deci and Ryan, 2004, 2008; Seymour et al., 2021), so self-determination in physical exercise is the autonomous motivation to motivate individuals to exercise. According to self-determination theory, autonomous motivation includes identified regulation, integrated regulation, and intrinsic motivation. The higher the intrinsic motivational orientation, the higher the concentration, persistence, and willingness to exert effort (Deci and Ryan, 1985). Specific to creativity, the influence of motivation on creativity is achieved through the integration of the individual's intrinsic and extrinsic motivations and environment (Hao and Tang, 2017). Therefore, motivation combined with specific activities, such as physical exercise, is more beneficial and enhances creativity. Moreover, autonomous motivation provides more freedom than controlled motivation, allowing individuals to think more broadly and promoting creativity (Eisenberger and Shanock, 2003). Thus, self-determination in physical exercise may relate to one's creativity.
In addition, from the perspective of individual cognitive development and information processing, creativity depends to some extent on the development and maturity of cranial nerves, including the cognitive processing such as information processing, control, and monitoring, and requires the coordination of the perceptual system, memory, thinking, and speech to perform the corresponding creative functions (Urban, 1991; Feldman, 1999). Self-determination enables individuals actively and frequently to participate in physical exercise (Seymour et al., 2021). Physical exercise changes the level of activation of brain regions such as the anterior cingulate gyrus and frontal lobe, ultimately enhancing cognitive abilities such as central executive function (Xia et al., 2018). Thus, self-determination in physical exercise may have a promoting effect on creative performance.
Specific to the relationship between self-determination in physical exercise and creative personality, previous studies pointed out that physical exercise was linked with an individual's personality (Rhodes, 2006; Rhodes and Pfaeffli, 2012; Wilson and Dishman, 2015; Sutin et al., 2016; Buhaş and Stance, 2017). Compared to individuals with less physical activity, individuals with more physical activity have significantly higher extroversion, neuroticism, conscientiousness, and openness (Wilson and Dishman, 2015). Prior studies also showed that extraversion and conscientiousness were both associated with more intrinsic regulation of exercise behaviors and less external regulation (Ingledew et al., 2004). These results indicated a close relationship between the intrinsic motivation of sports and individual personality characteristics. Moreover, the theory of integrating traits indicated that traits were tools for satisfying basic psychological needs of self-determination; basic psychological needs of self-determination can (partially) explain traits (Prentice et al., 2019). Given that creative personality is the intrinsic basic of creativity and one of the personality traits, and self-determination is the autonomous driving force to meet the needs of physical exercise, it is reasonable to deduce that the self-determination in physical exercise could predict individual's creative personality. However, few empirical studies have directly explored the relationship between self-determination in physical exercise and creative personality. Based on the above theories, we point out the following hypothesis:
Hypothesis 1: Self-determination in physical exercise could positively predict creative personality.
Moderating Role of Positive Affect
Although self-determination in physical exercise was related to creative personality, it is unlikely that all individuals are influenced by this effect equally. Therefore, it is necessary to identify the potential moderators in the relationship between self-determination in physical exercise and creative personality. Despite the scarce empirical studies, it is reasonable that positive affect can be one of the moderators in the relationship between self-determination in physical exercise and creative personality.
The extent to which an individual has positive affect may also influence the relationship between self-determination in physical exercise and creative personality. The “broaden-and-build” theory of positive affect posits that positive affect broadens people's momentary reserve of thinking activities, and helps individuals build their lasting personal resources (Zhang et al., 2017), thereby increasing individuals' creativity. Moreover, previous studies found that the positive affect moderated the relationship between managerial creativity and organizational performance; creativity in management could positively predict organizational performance when individuals experienced more positive affect (Yu et al., 2021). Nevertheless, when creative personality is associated with motivation, the moderating direction of emotion may be changed. A study pointed out that low positive affect in approach motivation enhances memory for peripherally presented information. Higher positive affect hinders the processing of general information (Gable and Harmon-Jones, 2010b). In other words, individuals with a lower level of positive affect are more likely to transform motivation (e.g., physical exercise self-determination) into the exploration of creative activities (e.g., risk-taking and curiosity). Thus, it is theoretically logical to assume that positive affect can moderate the relationships between self-determination in physical exercise and creative personality. However, no studies have examined the moderating effect of positive affect in the relationships between self-determination in physical exercise and creative personality. Based on the literature discussed above, the following hypothesis was established:
Hypothesis 2: Positive affect would moderate the relationships between self-determination in physical exercise and creative personality.
The Present Study
In summary, the purposes of the study were as follows. First, this study tested whether self-determination in physical exercise would positively affect college students' creative personality. Second, the study explored whether positive affect would moderate the relationship between self-determination in physical exercise and creative personality.
Materials and Methods
Participants
We recruited 1,201 college students (73.11% of the participants were female) from the capital normal university in Beijing, China. The average age of the participants was 20.10 years (SDage = 0.93, range = 17–27 years), with 59.03% of the students were freshmen, and the rest were sophomore. The survey includes demographic variables, physical exercise self-determination questionnaires, Williams Creativity Assessment Packet, and the positive affect frequency scale. In addition, we investigated the frequency and average duration of participants' physical activities. The results were presented in Figure 1.
Figure 1. The descriptive statistics of college students' physical exercise.
Measures
The Physical Exercise Self-determination Scale
The self-determination in physical exercise was measured by the Chinese version of the Physical Exercise Self-Determination Scale (Fang et al., 2012). The scale consists of 16 items that cover four dimensions: the sense of belonging and identification (e.g., “Physical exercise is good for my coursework”), body self-confidence (e.g., “My fit body is attractive during physical exercise”), sense of competence (e.g., “I have good sports knowledge and skills”), and sense of internal integration (e.g., “Physical exercise is my hobby, and I enjoy it”). The last item was reverse scored. Each item was rated on a 5- point Likert scale from 1 (strongly disagree) to 5 (strongly agree), with higher scores indicating higher levels of self-determination in physical exercise. This scale was used in previous studies (Wang et al., 2019). The scale has good reliability (the Cronbach's α is 0.937) and validity, with the fit indices of modified model is acceptable (RMSEA = 0.069 < 0.08, CFI = 0.965 > 0.90, and SRMR = 0.042 < 0.08).
The Positive and Negative Affect Schedule (PANAS)
The positive affect was measured by the Chinese version of Positive and Negative Affect Schedule (PANAS) (Yan et al., 2002) revised based on based on the original version (Watson et al., 1988; Diener et al., 1995; Huebner and Dew, 1995). The scale consists of 14 items covering positive affect and negative affect. We use the dimensions of positive affect to measure one's positive affective. The scale consists of 6 words describing positive affect (e.g., “pleasure,” “happiness,” and “Proud”), and the participants were asked to answer the frequency of these types of affects that they experienced most of the time. Each item was rated on a 7- point Likert scale from 1 (never) to 7 (always), with higher scores indicating higher levels of the positive affect. The scale has good reliability (the Cronbach's α is 0.871) and validity, with the fit indices of modified model is acceptable (RMSEA = 0.073 < 0.08, CFI = 0. 965 > 0.90, and SRMR = 0.074 < 0.08).
Williams Creativity Assessment Packet
The creativity was measured by the Chinese version of Williams creativity assessment packet (Lin and Wang, 1997) revised based on the original version (Williams, 1980). The scale consists of 50 items that cover four dimensions: risk-taking (e.g., “At school, I like to try to make guesses about things or questions, even if I do not necessarily guess them right, it does not matter”), curiosity (e.g., “I like to look carefully at things I have not seen before to learn more about them”), imagination (e.g., “I like to imagine things I want to know or do”), and challenge (e.g., “I like varied and imaginative stories”). Each item was rated on a 3- point Likert scale from 1 (complete non-conformity) to 3 (complete conformity), with a higher score indicating higher levels of the risk-taking, curiosity, imagination, challenge and creative personality. The scale has good reliability (the Cronbach's α is 0.902) and validity, with the fit indices of modified model is acceptable (RMSEA = 0.040 < 0.08, CFI = 0. 901 > 0.90, and SRMR = 0.047 < 0.08).
Procedure
This study provided a web-based survey platform for participants to voluntarily fill out the anonymous' survey and spent approximately about 5–10 min. The Ethics in Human Research Committee of the first author's university approved all materials and procedures. We also informed participants of the purpose of the study and the principles of voluntary participation and withdrew from the survey. Finally, we obtained informed consent from the participants.
Data Analysis
First, the descriptive statistics, correlation analysis, and regression analysis were conducted using SPSS 25.0. Second, we conducted model 1 of the PROCESS macro 3.3 for SPSS to determine the moderating effects of the positive affect between self-determination in physical exercise and creativity (Hayes, 2017). Third, we performed confirmatory factor analysis on the scales and tested the fitting index of the moderation model by Mplus 8.0. The models were acceptable if RMSEA < 0.08, the CFI > 0.90, and the SRMR < 0.08 (Bentler, 1990; Browne and Cudeck, 1992; Hu and Bentler, 1999). Finally, we used the SPSS macro “Interaction and simple slopes test with two continuous variables” to generate the plots and simple slopes analyses (Hayes, 2017).
Results
Common Method Bias Analysis
This study used self-reported data, so there may be a common method bias problem (Siemsen et al., 2010). This study used reverse scoring of some items to control common method bias. Then, Harman's single-factor test showed that 14 factors with characteristic roots greater than one were extracted from the unrotated exploratory factor analysis results, and the maximum factor variance explanation rate was 20.7% (<40%) which met the test criteria. Therefore, there was no severe common method bias in this study.
Preliminary Analyses
The descriptive statistics and correlation analysis for all study variables are presented in Table 1. The results showed that college students with a high level of self-determination in physical exercise were more likely to have a high level of creative personality (r = 0.28, p < 0.001), risk-taking, curiosity, imagination, and challenge (r = 0.13–0.34, p < 0.001). Besides, college students with high level of positive affect were more likely to have high level of creative personality (r = 0.33, p < 0.001), risk-taking, curiosity, imagination, challenge (r = 0.17–0.39, p < 0.001) and self-determination in physical exercise (r = 0.46, p < 0.001). In addition, college students with a high level of creative personality were more likely to have a high sense of belonging and identification, sense of competence, and body self-confidence (r = 0.20–0.31, p < 0.001).
Table 1. Means, standard deviations, and Pearson-correlations among variables.
The Predictive Effect of Self-determination in Physical Exercise on Creative Personality
In Hypothesis 2, the study expected that self-determination in physical exercise would predict creative personality. Regression analysis was conducted using SPSS 25.0 to test the predictive effect of self-determination in physical exercise on creative personality. As shown in Table 2, after controlling for gender and grade, the regression analysis results showed that self-determination in physical exercise significantly positively predicted creative personality (β = 0.285, p < 0.001). In addition, self-determination in physical exercise significantly positively predicted the risk-taking (β = 0.340, p < 0.001), curiosity (β = 0.289, p < 0.001), challenge (β = 0.239, p < 0.001), and imagination (β = 0.134, p < 0.001) separately. Thus, Hypothesis 1 was supported.
Table 2. Hierarchical regression analysis of creative personality and its dimensions on self-determination in physical exercise.
The Moderating Role of Positive Affect
In Hypothesis 2, the current study assumed that positive affect would moderate the relationship between self-determination in physical exercise and creative personality. To examine the moderated hypothesis, we used Model 1 in the SPSS macro program PROCESS developed by Hayes to examine the moderating effect (Hayes, 2017). Moreover, we further construct moderation model in latent variables, and the results showed that the fitting index of the modified moderation model is acceptable (RMSEA = 0.078 < 0.08, CFI = 0. 961 > 0.90 and SRMR = 0.043 < 0.08). As presented in Table 3, the moderation results showed that positive affect moderated the link between self-determination in physical exercise and creative personality (β = −0.088, p < 0.001). In addition, we further tested the moderating effect of positive affect on the relationship between self-determination in physical exercise and risk-taking, curiosity, challenge, and imagination. The results showed that positive affect separately moderated the relationship between self-determination physical exercise and risk-taking (β = −0.079, p < 0.01), curiosity (β = −0.095, p < 0. 001), challenge (β = −0.066, p < 0.05), and imagination (β = −0.058, p < 0.05).
Table 3. Regression analysis results of the moderating effect of positive affect.
Furthermore, we conducted a simple slope analysis on the link between self-determination in physical exercise and creative personality at two levels of positive affect (Table 4). According to Table 4, we plotted predicted self-determination in physical exercise against creative personality (Figure 2) separately for low and high levels of positive affect (1 SD below the mean and 1 SD above the mean, respectively). Simple slope tests indicated that for low positive affect individuals, higher levels of self-determination in physical exercise were associated with higher creative personality individuals (bsimple = 0.266, p < 0.001). However, for high positive affect individuals, the relationship between self-determination in physical exercise and creative personality was weakened (bsimple = 0.091, p < 0.05). Thus, Hypothesis 2 was supported.
Table 4. Simple slope analysis of interaction between self-determination in physical exercise and positive affect.
Figure 2. The relationship between self-determination in physical exercise and creative personality for high and low levels of positive affect. N = 1,201, SDPE, Self-determination in physical exercise.
Discussion
Little research focuses on the relationship between self-determination in physical exercise and creative personality, and the moderating mechanisms underlying this relationship are still largely unknown. To fill this gap, this study used the regression analysis to investigate the relationship between self-determination in physical exercise and creative personality and the moderating effect of positive affect on the links between self-determination in physical exercise and creative personality. The results revealed that physical exercise self-determination could positively predict creative personality, such as risk-taking, curiosity, challenge, and imagination. Positive affect moderated the relationship between self-determination in physical exercise and creative personality. We will discuss each of the findings in the following sections.
Self-determination in Physical Exercise and Creative Personality
The current study found that self-determination in physical exercise positively predicts creative personality, including risk-taking, curiosity, challenge, and imagination. To our knowledge, intrinsic motivation is an essential source of self-determination, and it plays a positive role in promoting creativity (Amabile et al., 1994; Hennessey, 2000; Eisenberger and Shanock, 2003). In sports, studies have confirmed that physical exercise self-determination, as intrinsic motivation, has a positive predictive effect on physical exercise behavior (Xiang, 2013). In addition, compared to individuals with less physical exercise, individuals with more physical exercise have higher extroversion, openness, and conscientiousness (Wilson and Dishman, 2015). The personality traits of extroversion and openness contribute to risk-taking, curiosity, challenge, and imagination (Ellis and Meneely, 2015; Li et al., 2015). From the perspective of sports, exercisers are more likely to try new things and new ways to challenge and surpass themselves and thus enhance themselves physically, intellectually, and effectively, which has an impact on creative personality, such as risk-taking, challenge, and curiosity (Bailey and Morley, 2006).
According to the basic psychological need theory, individuals have three basic psychological needs: autonomy, competence, and relatedness (Deci and Ryan, 2000, 2004). Physical exercise could achieve autonomous participation, role competence, and a sense of collective belonging. After meeting individuals' psychological needs, individuals will pursue higher needs, which can become a driving force for creativity. Therefore, it is logical that the relationship between the performance of creative personality and self-determination in physical exercise.
Moreover, the sense of belonging and identification, internal integration, body confidence, and competence in physical exercise also could positively predict creative personality. The sense of belonging and identification is an individual's conscious evaluation of behavioral goals or rules (Fang et al., 2012). When an individual comprehensively evaluation the importance of the behavior to himself or herself and can identify these rules, helping build the individual's creative personality. Competency refers to an individual's belief in his or her ability to perform the behavior competently (Fang et al., 2012). Individuals with solid competence and body confidence show a high sense of self-efficacy, so they have a stronger creative personality, such as curiosity and risk-taking (Karwowski, 2012, 2016). Internal integration refers to the behavior caused by the pleasure and satisfaction generated by the exercise activity itself, without the involvement of external conditions and complete assimilation of the rules identified by the self (Fang et al., 2012). As we mentioned above, intrinsic motivation and creativity are closely related, so individuals with a high level of internal tend to have a higher level of creative personality.
Previous research has focused on physical exercise activity or health status on creativity. Few studies have examined the influence of physical exercise self-determination on creativity and the moderating effect of positive affect. This study makes a unique contribution to dependent and independent variable indicators, which can provide empirical evidence for studies related to physical education and creativity development.
The Moderating Role of Positive Affect
This study showed that positive affect had a negative moderating effect on the relationship between self-determination in physical exercise and creative personality. Specifically, compared to individuals with having more positive emotions, the relationship between self-determination in physical exercise and creative personality was stronger with individuals having less positive emotions. These results may be attributed to the following reasons.
The affective-motivational dimension model holds that lower positive affect may be more likely to integrate various environmental cues and exhibit exploratory behaviors and activities. In comparison, higher positive affect reduces the breadth of attention. It hinders the brain from receiving peripheral information, thereby influencing the understanding of the whole and thus decreasing the level of cognition (Lu et al., 2002; Gable and Harmon-Jones, 2008, 2010a). This suggests that the effect of positive affect on creativity may be complex (Fernández-Abascal and Díaz, 2013). A prior study showed that low survival motivational affect could improve creativity, and it may be that the processing of affect requires the consumption of attentional resources (Pessoa and Engelmann, 2010). In terms of physical activities, in collective ball games, calm and collected athletes are often better at spotting the weaknesses of their opponents, making objective and rational judgments and decisions, and promptly adjusting their strategies to defeat their opponents. This suggests that lower positive emotions may be more conducive to improving creativity through exercise.
Implications and Limitations
The findings of the study have several important theoretical and practical implications. First, from a theoretical perspective, these findings provide insights into how self-determination physical in exercise was related to college students' creative personality, enriching and broadening people's understanding of self-determination theory and the literature on creativity. Given that self-determination and physical exercise are both powerful driving forces of individuals' creativity, it is essential to understand the self-determination in physical exercise's relationship with people's creative personality. Second, the findings showed that positive affect influenced the relationship between self-determination in physical exercise and creative personality. It enlightens us that the relationship between self-determination in physical exercise and creative personality is not constant and will be affected by individual emotions. Although positive emotion has been proved to be conducive to creativity in most previous studies, its role may be more complex and flexible when it acts as a moderator variable. Third, the present study might be helpful for the educator to increase students' intrinsic motivation to participate in physical exercise and cultivate students' creativity from the perspective of physical exercise, which realizes the improvement of college students' health and creativity.
Limitations and Future Directions
This study has some limitations, which need to be further improved in the future. First, the sample was collected from only one college in Beijing, so the sample's representativeness needs to be improved. Future research could use diverse samples to confirm these results. Second, this study was a cross-sectional design, so the causal or bidirectional relationship between creative personality and physical exercise was unable to be verified. Future research could use the longitudinal research design to examine further the effect of self-determination in physical exercise on creative personality. Third, the mechanism of influence on the relationship between self-determination in physical exercise and creative personality is not clear. Future research could collect more variables to examine how self-determination in exercise was related to creative personality.
Conclusion
This study indicates that self-determination in physical exercise can be a protective factor in college students' creative personality. Moreover, positive affect has a negative moderating effect on the relationship between self-determination in physical exercise and college students' creative personality. Specifically, a low level of positive affect could be a favorable factor in influencing the relationship between self-determination in physical exercise and creative personality.
Data Availability Statement
The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author.
Ethics Statement
The studies involving human participants were reviewed and approved by the Ethics in Human Research Committee of the first author's university. The patients/participants provided their written informed consent to participate in this study.
Author Contributions
SC and QW designed the study, analyzed the data, and wrote the manuscript. XW, LH, and DZ performed the investigation and analyzed the data. BS analyzed the data. All authors contributed to the article and approved the submitted version.
Funding
This work was supported by the Beijing Social Science Foundation, Key Project of Social Science Plan of Beijing Municipal Commission of Education (SZ202210028016).
Conflict of Interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Publisher's Note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Acknowledgments
We are grateful to all study participants for their contributions.
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Keywords: physical exercise, self-determination, creative personality, positive affect, college student
Citation: Chen S, Wang Q, Wang X, Huang L, Zhang D and Shi B (2022) Self-determination in Physical Exercise Predicts Creative Personality of College Students: The Moderating Role of Positive Affect. Front. Sports Act. Living 4:926243. doi: 10.3389/fspor.2022.926243
Received: 22 April 2022; Accepted: 20 June 2022;
Published: 11 July 2022.
Edited by:
Camila Vieira Ligo Teixeira, University of Maryland, Baltimore, United StatesReviewed by:
Marco Batista, Instituto Politécnico de Castelo Branco, PortugalIsadora Ribeiro, State University of Campinas, Brazil
Copyright © 2022 Chen, Wang, Wang, Huang, Zhang and Shi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Shaoqing Chen, YmxhbmtjaGVuJiN4MDAwNDA7MTYzLmNvbQ==
†These authors have contributed equally to this work and share first authorship