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REVIEW article

Front. Radiol.

Sec. Cardiothoracic Imaging

Volume 5 - 2025 | doi: 10.3389/fradi.2025.1552644

CT diagnosis and destiny of acute aortic intramural hematoma

Provisionally accepted
Giacomo Sica Giacomo Sica 1*Gaetano Rea Gaetano Rea 1Roberta Lieto Roberta Lieto 1Mariano Scaglione Mariano Scaglione 2Ahmad Abu-Omar Ahmad Abu-Omar 3Giorgio Bocchini Giorgio Bocchini 1Federica Romano Federica Romano 1Salvatore Masala Salvatore Masala 2Stefania Tamburrini Stefania Tamburrini 4Salvatore Guarino Salvatore Guarino 1Candida Massimo Candida Massimo 1Tullio Valente Tullio Valente 1
  • 1 Radiology Unit, Monaldi Hospital, Naples, Italy
  • 2 Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy
  • 3 University of British Columbia, Vancouver, British Columbia, Canada
  • 4 ASL Napoli 1 Centro, Napoli, Italy

The final, formatted version of the article will be published soon.

    Acute aortic intramural hematoma (IMH) is a relatively uncommon but potentially life-threating aortic disease that can occur primarily in hypertensive and atherosclerotic patients. The course of IMH varies widely, with the condition either regressing, remaining stable, or progressing until it leads to outward rupture or intimal layer disruption, eventually resulting in overt aortic dissection. Therefore, poor prognostic computed tomography (CT) features must be promptly recognized and and reported by the radiologist. In emergency departments, readily accessible non-invasive CT angiography is crucial for achieving a rapid and accurate diagnosis, essential for appropriate management. As for Type A and B aortic dissection, surgery is typically recommended in Western countries for patients with Stanford Type-A IMH, as well as those experiencing irrepressible pain. For Stanford Type-B IMH patients without complications or an incessant pain, medical treatment is suggested but with imaging follow-up. In complicated Stanford Type B situations, Thoracic Endovascular Aortic Repair (TEVAR) is currently indicated. Aim of this review is to present pathophysiology, CT diagnosis and IMH fate, providing the reader CT image-based review of the CT diagnostic criteria, complications and associated critical prognostic findings of this rather rare aortic disease.

    Keywords: Aortic intramural hematoma, Computed Tomography Angiography (CTA), Acute aortic syndrome (AAS), Penetrating atherosclerotic ulcer (PAU), Aortic dissection (AD), diagnosis

    Received: 20 Jan 2025; Accepted: 13 Feb 2025.

    Copyright: © 2025 Sica, Rea, Lieto, Scaglione, Abu-Omar, Bocchini, Romano, Masala, Tamburrini, Guarino, Massimo and Valente. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Giacomo Sica, Radiology Unit, Monaldi Hospital, Naples, Italy

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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