AUTHOR=Gadermayr Michael , Heckmann Lotte , Li Kexin , Bähr Friederike , Müller Madlaine , Truhn Daniel , Merhof Dorit , Gess Burkhard TITLE=Image-to-Image Translation for Simplified MRI Muscle Segmentation JOURNAL=Frontiers in Radiology VOLUME=1 YEAR=2021 URL=https://www.frontiersin.org/journals/radiology/articles/10.3389/fradi.2021.664444 DOI=10.3389/fradi.2021.664444 ISSN=2673-8740 ABSTRACT=

Deep neural networks recently showed high performance and gained popularity in the field of radiology. However, the fact that large amounts of labeled data are required for training these architectures inhibits practical applications. We take advantage of an unpaired image-to-image translation approach in combination with a novel domain specific loss formulation to create an “easier-to-segment” intermediate image representation without requiring any label data. The requirement here is that the task can be translated from a hard to a related but simplified task for which unlabeled data are available. In the experimental evaluation, we investigate fully automated approaches for segmentation of pathological muscle tissue in T1-weighted magnetic resonance (MR) images of human thighs. The results show clearly improved performance in case of supervised segmentation techniques. Even more impressively, we obtain similar results with a basic completely unsupervised segmentation approach.