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ORIGINAL RESEARCH article
Front. Public Health
Sec. Aging and Public Health
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1569119
This article is part of the Research Topic Atopic March and Atopic Multimorbidity View all 5 articles
Global, regional, and national burden of elderly atopic dermatitis in 204 countries and territories worldwide
Provisionally accepted- First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Background: With the aging global population, elderly atopic dermatitis (AD) is emerging as an increasingly significant health challenge. This study aimed to evaluate the global burden of elderly AD from 1990 to 2021 and to project its change to 2050.The estimates and 95% uncertainty intervals of prevalence, incidence, and disabilityadjusted life-years (DALYs) attributable to AD among individuals aged over 60 years were extracted from the Global Burden of Diseases (GBD) Study 2021. We used joinpoint regression analysis, decomposition analysis, cross-country inequality analysis, frontier analysis and prediction model to epidemiological analysis.From 1990 to 2021, the global prevalence of elderly AD increased to 11009630 cases (95% UI: 9915829 to 12170941), even as ASRs declined, which were primarily driven by population growth. It was observed that females and 75-79 years old had higher incidence rates. SDI relative and frontier analysis exhibited that incidence, prevalence and DALYs rates were positively correlated with SDI levels, while SDI-related inequalities had a significant decrease. Predictions up to 2050 anticipated increasing elderly AD incidence, prevalence, and DALYs numbers, while only agestandardized disability-adjusted life-year rates (ASDRs) were expected to decline.The burden of elderly AD varied by genders, age groups, regions, countries and climatic conditions. Although the ASRs had shown a decline over time, the burden of elderly AD remained significant, especially in regions with high SDI levels. In the future, the burden of elderly AD was projected to continue rising until 2050, thereby targeted interventions and public health strategies were needed to address this trend.
Keywords: atopic dermatitis1, the elderly2, Global Burden of Disease Study3, Disabilityadjusted life years4, Incidence5
Received: 31 Jan 2025; Accepted: 20 Mar 2025.
Copyright: © 2025 Ou, Shao, Zhang and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jingbo Zhang, First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Jin Chen, First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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