ORIGINAL RESEARCH article
Front. Public Health
Sec. Infectious Diseases: Epidemiology and Prevention
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1550565
This article is part of the Research TopicTowards Control of the HIV epidemic: Trends in Epidemiology and Emerging Drug Resistance in the Integrase Inhibitor EraView all articles
HIV transmission risk among people living with HIV in Zhejiang Province, China: data from a large cross-sectional study, 2022
Provisionally accepted
- Zhejiang Center for Disease Control and Prevention (Zhejiang CDC), Hangzhou, China
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Background: Effective management of people living with HIV (PLWH) can block the sexual transmission as there is a zero risk of sexual transmission (by U=U campaign); however, few studies have aimed to addressed the risk of transmission among people living with HIV (PLWH) in China.We conducted a cross-sectional survey among PLWH in 2022. PLWH were categorized into four HIV transmission risk groups: on antiretroviral therapy (ART) and HIV viral load (VL) <50 copies/mL as minimum risk; on ART and 50VL<1000 copies/mL as low-risk; on ART and VL1000 copies/mL, or on ART but without VL testing as medium-risk; not on ART as high-risk. Multivariable logistic regression was used to identify risk factors associated with risk of HIV transmission.Result: A total of 39,744 PLWH were enrolled in the study. The proportion of those at risk for HIV transmission was 11.4%: low-risk 3.4%, medium-risk 6.9% and high-risk 1.1%. 33,764 (95.0%) patients were tested for syphilis, of whom 5.6% (1,879) had a current syphilis infection. Multivariable logistic regression analysis showed that compared with patients at minimum risk of transmission, individuals who were male (adjusted odds ratio [aOR]: 1.17, 95% confidence interval [
Keywords: Human immunodeficiency virus (HIV), People living with HIV, transmission risk, antiretroviral therapy, Viral Load
Received: 23 Dec 2024; Accepted: 21 Apr 2025.
Copyright: © 2025 He, PAN, Yang, Zheng, Cheng and Chai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: XIAOHONG PAN, Zhejiang Center for Disease Control and Prevention (Zhejiang CDC), Hangzhou, China
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