ORIGINAL RESEARCH article

Front. Public Health

Sec. Radiation and Health

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1547101

Predictive Modeling of Eye Lens Dose in Interventional Radiology: A Quadratic Polynomial Regression Approach to Cumulative Fluoroscopy Dose

Provisionally accepted
Mengyun  WuMengyun Wu1Fang  YuanFang Yuan1Yeqing  GuYeqing Gu2Jinhan  WangJinhan Wang2Lin  LuLin Lu3*ZHI  ZENGZHI ZENG4*
  • 1Chongqing Center for Disease Control and Prevention, Chongqing, Chongqing, China
  • 2Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
  • 3Southwest University of Political Science & Law, Chongqing, Chongqing, China
  • 4Chinese Center For Disease Control and Prevention, Beijing, China

The final, formatted version of the article will be published soon.

Objectives: This study aimed to investigate the relationship between cumulative fluoroscopy dose and eye lens radiation dose among interventional radiologists, and to develop a predictive model to enhance occupational radiation safety.Methods: We collected data from interventional radiologists, focusing on cumulative fluoroscopy dose during procedures and corresponding eye lens doses. A quadratic polynomial regression model was developed to assess the non-linear relationship between cumulative fluoroscopy dose and eye lens dose. The study involved the use of machine-generated cumulative dose data and personal eye lens dosimeters.Results: The quadratic polynomial regression model effectively captured the non-linear relationship for cumulative doses >20 Gy, enabling precise dose prediction at higher exposure levels where cataract risks escalate. However, the model showed limited accuracy for doses ≤20 Gy. This model allowed for more precise prediction of eye lens dose, particularly at higher exposure levels where the risks of radiation-induced cataracts increase significantly.Conclusions: The quadratic polynomial regression model serves as a potentially valuable tool for real-time monitoring in high-exposure scenarios (>20 Gy), supporting radiation safety protocols in clinical practice. Integration into routine hospital systems may enhance radiation protection protocols and inform policy development, aligning occupational dose monitoring practices with international safety standards.

Keywords: interventional radiology, Eye lens dosimetry, Cumulative Fluoroscopy Dose, quadratic polynomial regression, Occupational radiation safety

Received: 20 Dec 2024; Accepted: 24 Apr 2025.

Copyright: © 2025 Wu, Yuan, Gu, Wang, Lu and ZENG. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Lin Lu, Southwest University of Political Science & Law, Chongqing, 400031, Chongqing, China
ZHI ZENG, Chinese Center For Disease Control and Prevention, Beijing, China

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