Peer support to improve the Internet-based HIV self-testing kits secondary distribution among men who have sex with men in Zhuhai, China

Hang Lyu¹Yuxin Ni^2,3Xi He⁴Ying Lu²Dongya Wang²Xinxue Yu⁵Weiming Tang^2,6*Yi Zhou^1,7*

• ¹Zhuhai Center for Disease Control and Prevention, Zhuhai, China
• ²University of North Carolina Project-China, Guangzhou, China
• ³Department of Health Law, Policy & Management, School of Public Health, Boston University, Boston, United States
• ⁴Zhuhai Xutong Voluntary Services Center, Zhuhai, Guangdong Province, China
• ⁵Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China
• ⁶Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China
• ⁷Faculty of Medicine, Macau University of Science and Technology, Macau, Macao, SAR China

Support from peers is a commonly employed behavioural prevention approach aimed at key populations to enhance HIV prevention efforts. Internet-based HIV self-testing (HIVST) has been widely used among men who have sex with men (MSM) across China over the past few years.Objective: We aimed to analyze the occurrence of Internet-based peer support and high-risk behaviours during the process of distributing HIVST kits among MSM.The single-arm prospective cohort study was conducted among MSM in Zhuhai, China. The study utilized an HIVST online ordering system based on WeChat developed by Xutong. MSM who ordered HIVST kits and distributed to people in their network for self-testing were defined as index participants. People who received the kits from the index participants and providing testing results were defined as alters. Chi-squared tests were used to compare baseline and follow-up characteristics of the participants. Cramer's V was used to quantify the level of association between the Internet-based HIVST and condomless anal sexual behaviors among index participants. Logistic regression analysis was used to evaluate factors associated with peer support among alter participants. A p < 0.05 was regarded as statistically significant.Results: A total of 288 index participants the study and they distributed HIVST kits to 478 alters.In the study, 84.0% (242/288) of the index participants reported that they provided peer support to their alters, and 87.4% (418/478) of the alters reported receiving peer support from the index participants. As for the alters, 19.9% (95/478) had sex with index participants on the day of HIVST. Among them, 24.2% (23/95) had sex after the HIVST, and 72.6% (69/95) used a condom during sex. Index participants who had been asked for advice about HIV and other sexually transmitted infections were more likely to provide peer support to alters (OR: 1.85, 95% CI: 1.01-3.37).This study has enhanced our understanding of the occurrence of peer support and high-risk behaviours during the process of HIVST kits secondary distribution, and provided evidence that Internet-based HIVST appears to be a promising approach for behaviours interventions among MSM.