The final, formatted version of the article will be published soon.
ORIGINAL RESEARCH article
Front. Public Health
Sec. Children and Health
Volume 13 - 2025 |
doi: 10.3389/fpubh.2025.1512403
This article is part of the Research Topic The Impact of Climate and Environmental Change on Epigenetics and Pediatric Health View all 3 articles
Influence of Meteorological and Environmental Factors on Pediatric Urinary Tract Infections: Insights from a Six-Year Retrospective Study in Central China
Provisionally accepted- Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Objectives: To investigate the association between meteorological factors and common uropathogens in children with urinary tract infections (UTIs) and assesses the potential influence of weather conditions on pediatric UTIs.Analyze the demographic and uropathogen characteristics from children with culture-proven UTIs and its correlation with meteorological factors.Methods: 2411 data from infants and children with UTIs in a children's hospital from 2016 to 2021 were retrospectively analyzed. A correlation analysis was conducted to investigate the relationship between the monthly detection number of uropathogens and meteorological factors.Results: Multiple linear stepwise regression analyses showed a positive correlation between monthly average temperature, precipitation volume, sunshine hours, monthly total number of uropathogens, and the number of E. coli and E. faecalis. E. faecium was predominant in <12-month-old children, while E. coli was dominant in the 3-18year age category. E. faecium showed a higher prevalence in girls, while E. faecalis was more prevalent in boys. E. coli exhibited resistance rates of >40% to second-or third-generation cephalosporins in multiple age groups. E. faecium showed high resistance rates to tetracyclines, fluoroquinolones, erythromycin, ampicillin, and penicillin, while K. pneumoniae displayed higher sensitivity to cephalosporinsulbactam and amikacin, but higher resistance rates to cefazolin and ceftazidime.This study reveals the association between meteorological factors and uropathogens in children with UTIs, as well as the distribution, age-related characteristics, gender differences and antibiotic resistance profiles of pathogenic bacteria. These findings inform the development of targeted strategies for UTI prevention and treatment based on uropathogenic characteristics and meteorological conditions.
Keywords: pediatric urinary tract infections, Uropathogens, Distribution characteristics, Meteorological factors, antibiotic resistance, Retrospective study
Received: 16 Oct 2024; Accepted: 31 Jan 2025.
Copyright: © 2025 wang, Li, tang and Xi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
xiaomei wang, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.