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ORIGINAL RESEARCH article
Front. Public Health
Sec. Aging and Public Health
Volume 13 - 2025 |
doi: 10.3389/fpubh.2025.1506368
Relationship between TyG-related index and hearing loss in people over 45 s in China
Provisionally accepted
Chao Wang 1
Mengdi Shi 1* Liangzhen Xie 2* Chenhao Jiang 3* Yunxin Li 4* Jingxiao Li 1* Shulin Li 2* Yan Li 2*- 1 Heilongjiang University of Chinese Medicine, Harbin, China
- 2 First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China
- 3 Damao United Banner Mongolian Medical Hospital, Baotou, China
- 4 The second affiliated hospital of Heilongjiang University of Traditional Chinese medicine, harbin, China
Background: Triglycerides and fasting glycemic index are biomarkers used to assess the risk of insulin resistance and metabolic syndrome. It and its derivatives such as the TyG-BMI index are currently able to reflect the degree of insulin resistance and are closely related to a variety of metabolic diseases. The relationship between the TyG-BMI index and hearing loss remains underexplored, particularly in the context of aging and public health. This study investigates the association of the TyG index, BMI index, and TyG-BMI index with hearing loss, with a focus on their potential implications for the aging population. Methods: Data from the China Health and Retirement Longitudinal Study (CHARLS) database were analyzed using R software. We applied multi-factor logistic regression, linear regression, restricted cubic splines, and subgroup analyses to assess the impact of the TyG index, BMI index, and TyG-BMI index on hearing loss across different age groups. Results: The TyG index was not significantly associated with hearing loss. However, both the BMI index and the TyG-BMI index exhibited a positive correlation with hearing loss, particularly among older individuals. The results suggest that as the population ages, higher BMI and TyG-BMI indices may increase the risk of hearing impairment.While the TyG index does not show a significant link to hearing loss, higher BMI and TyG-BMI indices are associated with an increased risk of hearing loss, especially in older adults. These findings highlight the importance of considering aging-related factors in public health initiatives aimed at preventing hearing loss. Further research is needed to elucidate the mechanisms underlying these associations and to develop age-inclusive strategies for addressing hearing impairment in the aging population.
Keywords: BMI, TyG-BMI index, Aging-related, CHARLS, Hearing Loss
Received: 05 Oct 2024; Accepted: 20 Jan 2025.
Copyright: © 2025 Wang, Shi, Xie, Jiang, Li, Li, Li and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Mengdi Shi, Heilongjiang University of Chinese Medicine, Harbin, China
Liangzhen Xie, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China
Chenhao Jiang, Damao United Banner Mongolian Medical Hospital, Baotou, China
Yunxin Li, The second affiliated hospital of Heilongjiang University of Traditional Chinese medicine, harbin, China
Jingxiao Li, Heilongjiang University of Chinese Medicine, Harbin, China
Shulin Li, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China
Yan Li, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China
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