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SYSTEMATIC REVIEW article

Front. Public Health

Sec. Aging and Public Health

Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1505541

This article is part of the Research Topic Innovative Personalized Medicine Strategies for Managing Multi-Morbidity View all 3 articles

Risk Prediction Models for Mortality in Patients with Multimorbidity: A Systematic Review and Meta-analysis

Provisionally accepted
圆圆 陈 圆圆 陈 1meifen ji meifen ji 2lihong jin lihong jin 1*Luga Dong Luga Dong 1minhua chen minhua chen 1xuli shang xuli shang 1Heyuanyuan Heyuanyuan Heyuanyuan Heyuanyuan 1xiang lan xiang lan 1
  • 1 Lishui City People's Hospital, Lishui, China
  • 2 Zhejiang University, Hangzhou, Zhejiang Province, China

The final, formatted version of the article will be published soon.

    Numerous risk prediction models for mortality in patients with multimorbidity have been established; however, their quality and clinical applicability remain uncertain. This systematic review aimed to screen and systematically review published studies on existing risk prediction models for mortality in patients with multimorbidity. Overall, we included 18 studies with 21 prediction models. The included studies revealed a degree of discriminatory ability in predicting mortality in patients with multimorbidity; however, they all demonstrated significant risks of bias. Furthermore, because the major focus of our study aligns very well with the aims and scope of your esteemed journal, we believe that this paper will be of great interest to its wide readership. We believe that our study makes a significant contribution to the literature because our findings provide valuable insights for the future development of accurate prediction models for mortality in this patient population. Future re

    Keywords: Mortality, Risk prediction model, Systematic review, Meta-analysis, multimorbidity

    Received: 03 Oct 2024; Accepted: 06 Mar 2025.

    Copyright: © 2025 陈, ji, jin, Dong, chen, shang, Heyuanyuan and lan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: lihong jin, Lishui City People's Hospital, Lishui, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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