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ORIGINAL RESEARCH article
Front. Public Health
Sec. Health Economics
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1494229
Global, regional and national burden of decubitus ulcers in 204 countries and territories from 1990 to 2021: a systematic analysis based on the Global Burden of Disease Study 2021
Provisionally accepted- 1 City University of Hong Kong, Kowloon, Hong Kong, SAR China
- 2 Xinxiang Medical University, Xinxiang, Henan Province, China
- 3 Army Medical University, Chongqing, China
- 4 Wuhan Textile University, Wuhan, Hubei Province, China
Background: Decubitus ulcers, also known as pressure ulcers, pose a significant public health challenge due to their substantial impact on morbidity, mortality, and healthcare expenditures.Methods: The number and age-standardized rates (ASRs) of prevalence, death, disability adjusted life-year (DALY), years of life lost (YLL), and years lived with disability (YLD) at the global, regional, and national levels were acquired from the GBD 2021 database. Trends were evaluated based on the estimated average percentage change (EAPC) of ASRs. Additionally, data were stratified by socio-demographic index (SDI) quantiles, regions, countries, territories, and age groups.Results: The total number of decubitus ulcer cases increased from 300442 in 1990 to 645588 in 2021. The global ASR of prevalence decreased slightly from 8.25 to 7.92 per 100000 persons, with most cases occurring in individuals aged 60 and older. Deaths due to decubitus ulcers rose from 16622 in 1990 to 37033 in 2021, while the global ASR of death declined from 0.53 to 0.46 per 100000 persons. DALY due to decubitus ulcers increased, exhibiting significant variation across regions and age groups. A higher SDI was correlated with increased ASRs of prevalence (R = 0.488, P < 0.001) and YLD (R = 0.495, P < 0.001). Conversely, a higher SDI was correlated with lower ASRs of death (R = -0.329, P < 0.001), DALY (R = -0.398, P < 0.001), and YLL (R = -0.445, P < 0.001). Conclusions: The global burden of decubitus ulcers has risen, with notable regional and age-related disparities. This study offers valuable insights for policymakers to optimize healthcare strategies and mitigate the public health impact of decubitus ulcers.
Keywords: Decubitus ulcers, Pressure ulcers, Burden, Trends, systematic analysis
Received: 22 Oct 2024; Accepted: 14 Feb 2025.
Copyright: © 2025 Zhang, Wei, Han, Zhong, Lu and Niu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Zehao Niu, Army Medical University, Chongqing, China
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