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REVIEW article
Front. Public Health
Sec. Public Health Policy
Volume 13 - 2025 | doi: 10.3389/fpubh.2025.1453167
Consensus Based Recommendations for the Management of Post-COVID Long-Term Sequelae (Long COVID): A Regional Perspective
Provisionally accepted
Majid AlShamrani1
Fayssal Farahat1*
Abdullah Assiri2
Sami AlHajjar3Ali Albarrak4
Hashem AlHashemi5Mohammed AlZunitan6Meshal AlAqeel7Sami AlYami8Ziad A Memish9- 1King Abdulaziz Medical City; King Saud bin Abdulaziz University for Health Sciences; King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
- 2Ministry of Health, Riyadh, Saudi Arabia
- 3Pediatric Infectious Diseases, Department of Pediatrics, King Faisal Specialist Hospital and Research Center, College of Medicine , AlFaisal University Riyadh, Saudi Arabia, Riyadh, Saudi Arabia
- 4Internal Medicine and Infectious Diseases, Prince Sultan Military Medical City, Riyadh, Saudi Arabia
- 5King Abdulaziz Medical City; King Saud bin Abdulaziz University for Health Sciences; King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia
- 6King Abdulaziz Medical City, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
- 7Psychiatry Section, King Abdulaziz Medical City; King Saud bin Abdulaziz University for Health Sciences; King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
- 8Respiratory Medicine,King Abdulaziz Medical City, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
- 9Research and Innovation Center, King Saud Medical City, Ministry of Health & College of Medicine, Alfaisal University & Hubert Department of Global Health, Emory University, Atlanta, GA, 30322, USA, Riyadh, Saudi Arabia
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The coronavirus disease 2019 (COVID-19) pandemic marks the biggest public health emergency of the 21 st century. The long-term health issues linked to COVID-19, also known as Long COVID, pose a great challenge to patients and society. This article aims to highlight the current unmet clinical needs and present expert recommendations for region-specific assessment and management of Long COVID.A secondary desk research was performed focusing on global and regional guidelines for the assessment and management of Long COVID. The observations from the desk research form the foundation for the consensus statements. Additionally, an expert panel consisting of 10 consultant physicians from related specialties reviewed these guidelines and literature in advisory board meetings to identify unmet needs, bridge clinical gaps, and develop recommendations for the evaluation and management of Long COVID.The expert recommendation statements were drafted based on overarching principles for the clinical assessment and management of Long COVID. The overarching principles used a targeted, multidisciplinary approach, and collaboration between multiple specialties of healthcare. The panel also highlighted the value of holistic care for the management of Long COVID.Long COVID is a major public health challenge. These expert recommendations are expected to guide healthcare professionals in their clinical decision-making for the assessment, management, and appropriate rehabilitation of patients with Long COVID.
Keywords: Long COVID 1, post-acute sequelae of COVID-19 (PASC), Post COVID-19 condition (PCC), recommendations, Management
Received: 25 Sep 2024; Accepted: 11 Apr 2025.
Copyright: © 2025 AlShamrani, Farahat, Assiri, AlHajjar, Albarrak, AlHashemi, AlZunitan, AlAqeel, AlYami and Memish. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Fayssal Farahat, King Abdulaziz Medical City; King Saud bin Abdulaziz University for Health Sciences; King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.