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ORIGINAL RESEARCH article

Front. Public Health
Sec. Aging and Public Health
Volume 12 - 2024 | doi: 10.3389/fpubh.2024.1461300

Association between weight-adjusted waist circumference index and depression in older patients with hypertension: a study based on NHANES 2007-2016

Provisionally accepted
Yi Niu Yi Niu 1Yuqin Sun Yuqin Sun 1*Yijie Xie Yijie Xie 2*Shun Yu Shun Yu 2*
  • 1 Wuxi Medical College, Jiangnan University, Wuxi, China
  • 2 Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    Objective：Our aim was to assess the relationship between weight-adjusted waist circumference index (WWI) and the prevalence of depression in elderly hypertensive patients in the United States.We selected individuals from the National Health and Nutrition Examination Survey (NHANES) database from 2007 to 2016 and used logistic regression analyses, subgroup analyses, and dose-response curves to assess the associations between the WWI index and the prevalence of depression in older hypertensive patients with age, sex, and BMI.Results: A total of 4228 participants aged ≥60 years with hypertension were included in our study; 364 patients were assessed for depression. After correction for confounders, each unit increase in WWI increased the risk of depression in older hypertensive patients by 19% (OR=1.19, 95% CI: 0.99, 1.43). Dose-response curves showed that the WWI index was positively associated with the prevalence of depression in older hypertensive patients when the WWI index was ≥11.6. Based on subgroup analyses, this association was particularly pronounced in individuals ≥70 years of age, women, and individuals with a BMI of 25 or greater.Conclusions: Higher WWI scores were positively associated with the prevalence of depression in older hypertensive patients and correlated with genger, age and BMI. This is notable, although a causal relationship cannot be established at this time.

    Keywords: hypertension in the elderly, WWI Index, Depression, Cross-sectional study, NHANES (National Health and Nutrition Examination Survey)

    Received: 08 Jul 2024; Accepted: 04 Sep 2024.

    Copyright: © 2024 Niu, Sun, Xie and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yuqin Sun, Wuxi Medical College, Jiangnan University, Wuxi, China
    Yijie Xie, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, China
    Shun Yu, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, China

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