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SYSTEMATIC REVIEW article

Front. Public Health
Sec. Environmental Health and Exposome
Volume 12 - 2024 | doi: 10.3389/fpubh.2024.1440908
This article is part of the Research Topic Biological contaminants of concern in water and wastewater: An environmental health perspective View all 13 articles

Antimicrobial Resistance Profile of Escherichia coli in Drinking Water from One Health Perspective in Low and Middle Income Countries

Provisionally accepted
Belay Desye Belay Desye *Temeselew Woldetsadik Mawugatie Temeselew Woldetsadik Mawugatie Lakew Asmare Lakew Asmare Yawkal Tsega Yawkal Tsega Dagnachew Melak Dagnachew Melak Abel Endawkie Abel Endawkie Chala Daba Chala Daba
  • Wollo University, Dessie, Ethiopia

The final, formatted version of the article will be published soon.

    Introduction: Antimicrobial resistance is a major global public health concern, especially in low-resource settings. In low-and middle-income countries, the existing evidence about antimicrobial resistance in drinking water is inconsistence and not comprehensive. Therefore, this study aimed to estimate the pooled prevalence of antimicrobial resistance profiles of Escherichia coli from drinking water in low-and middleincome countries. Methods: This study was conducted using comprehensive literature searches using various databases such as PubMed, Scientific Direct, HINARI, and Google Scholar. Data extraction was performed using Microsoft Excel and exported to STATA 14/SE software for analysis. We used the Joanna Briggs Institute's quality appraisal tool to ensure the quality of the included studies. A random effects model was employed to estimate the pooled prevalence. Publication bias was evaluated using funnel plots and Egger's regression test. Subgroup and sensitivity analysis were also conducted in this study.The study found that the pooled prevalence of Escherichia coli isolates in drinking water was 37.94% (95% CI: 26.73-49.13). The prevalence of multidrug resistance was 43.65% (95% CI: 31.15-56.15). Regarding specific antimicrobials, the pooled resistance levels of Escherichia coli were 54.65% (95% CI: 41.35-67.96) against contrimoxazole, followed by 48.64% (95% CI: -3.6-101) against amoxicillin and 48% (95% CI: -18.1-114.2) against cefuroxime.The findings indicated a significant prevalence of antimicrobial resistance of Escherichia coli isolated from drinking water and its multidrug resistance. To address this issue, it recommends focusing on improving basic hygiene and sanitation practices and enhancing water and wastewater treatment systems.

    Keywords: 1145, Wollo university, Ethiopia Antimicrobial resistance, Escherichia coli, Drinking Water, One Health, Low and Middle Income Countries

    Received: 30 May 2024; Accepted: 19 Nov 2024.

    Copyright: © 2024 Desye, Woldetsadik Mawugatie, Asmare, Tsega, Melak, Endawkie and Daba. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Belay Desye, Wollo University, Dessie, Ethiopia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.