AUTHOR=Bizzotto Andrea , Guzzetta Giorgio , Marziano Valentina , Del Manso Martina , Mateo Urdiales Alberto , Petrone Daniele , Cannone Andrea , Sacco Chiara , Poletti Piero , Manica Mattia , Zardini Agnese , Trentini Filippo , Fabiani Massimo , Bella Antonino , Riccardo Flavia , Pezzotti Patrizio , Ajelli Marco , Merler Stefano TITLE=Increasing situational awareness through nowcasting of the reproduction number JOURNAL=Frontiers in Public Health VOLUME=12 YEAR=2024 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1430920 DOI=10.3389/fpubh.2024.1430920 ISSN=2296-2565 ABSTRACT=Background

The time-varying reproduction number R is a critical variable for situational awareness during infectious disease outbreaks; however, delays between infection and reporting of cases hinder its accurate estimation in real-time. A number of nowcasting methods, leveraging available information on data consolidation delays, have been proposed to mitigate this problem.

Methods

In this work, we retrospectively validate the use of a nowcasting algorithm during 18 months of the COVID-19 pandemic in Italy by quantitatively assessing its performance against standard methods for the estimation of R.

Results

Nowcasting significantly reduced the median lag in the estimation of R from 13 to 8 days, while concurrently enhancing accuracy. Furthermore, it allowed the detection of periods of epidemic growth with a lead of between 6 and 23 days.

Conclusions

Nowcasting augments epidemic awareness, empowering better informed public health responses.