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SYSTEMATIC REVIEW article

Front. Public Health
Sec. Infectious Diseases: Epidemiology and Prevention
Volume 12 - 2024 | doi: 10.3389/fpubh.2024.1423573
This article is part of the Research Topic Multidisciplinary Approaches in Pediatric Gastrointestinal and Liver Disease View all 6 articles

Rotavirus outbreaks in China, 1982-2021: A systematic review

Provisionally accepted
Tian Yi Tian Yi 1Yu Fan Yu Fan 2Zhang G. hua Zhang G. hua 3Tian C. yu Tian C. yu 4Wang X. xin Wang X. xin 5Chen Y. wei Chen Y. wei 1Yan H. qiu Yan H. qiu 1Lei Jia Lei Jia 1Zhang D. tao Zhang D. tao 1Quanyi Wang Quanyi Wang 1Zhiyong Gao Zhiyong Gao 1*
  • 1 Beijing Center for Disease Prevention and Control (Beijing CDC), Beijing, China
  • 2 The University of Hong Kong, Pokfulam, Hong Kong, SAR China
  • 3 Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing Municipality, China
  • 4 Children's hospital affiliated with the capital institute of pediatrics, Beijing, China
  • 5 Capital Medical University, Beijing, Beijing Municipality, China

The final, formatted version of the article will be published soon.

    Background: Rotavirus is globally recognized as an important cause of acute gastroenteritis in young children. Whereas previous studies focused more on sporadic diarrhea, the epidemiological characteristics of rotavirus outbreaks have not been systematically understood.Methods: This systematic review was carried out according to the Preferred Reporting Items for Systematic Review and Meta-Analysis standards, WANFANG, China National Knowledge Infrastructure (CNKI), PubMed, and Web of Science databases were searched from database inception to February 20, 2022. We used SPSS 21.0 statistical software for data analysis, RStudio1.4.1717, and ArcGIS trial version for plotting bar graphs and maps.Results: Among 1,596 articles, 78 were included, with 92 rotavirus outbreaks and 96,128 cases.Most outbreaks (67.39%, 62/92) occurred in winter and spring. The number of rotavirus outbreaks reported in the southern region was more than that in the northern region. Outbreaks were most commonly reported in villages (33/92, 35.87%), followed by hospitals (19, 20.65%). The outbreak duration was longer in factories, workers' living places, and villages, while it was shorter in hospitals.Waterborne transmission was the main transmission mode, with the longest duration and the largest number of cases. Rotavirus groups were identified in 66 outbreaks, with 40 outbreaks (60.61%) caused by Group B rotaviruses and 26 outbreaks (39.39%) caused by Group A rotaviruses. Significant differences were found in duration, number of cases, settings, population distribution, and transmission modes between Groups A and B rotavirus outbreaks.

    Keywords: Rotavirus1, Outbreak2, Epidemiological characteristics3, transmission4, genotypes5

    Received: 26 Apr 2024; Accepted: 29 Jul 2024.

    Copyright: © 2024 Yi, Fan, hua, yu, xin, wei, qiu, Jia, tao, Wang and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhiyong Gao, Beijing Center for Disease Prevention and Control (Beijing CDC), Beijing, 100009, China

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