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ORIGINAL RESEARCH article

Front. Public Health
Sec. Substance Use Disorders and Behavioral Addictions
Volume 12 - 2024 | doi: 10.3389/fpubh.2024.1418117

Relationship between Alcohol Use and Overactive Bladder Disease: A Cross-Sectional Study of the NHANES 2005 to 2016

Provisionally accepted
Xinyi Zhang Xinyi Zhang *
  • Fourth military medical university, Xi'an, China

The final, formatted version of the article will be published soon.

    Background: Overactive bladder syndrome (OAB) significantly affects quality of life, limiting daily activities and work productivity. Alcohol, a diuretic, may worsen urinary symptoms. Studies on alcohol's relationship with OAB have shown conflicting results. This study aimed to clarify this using a large, nationally representative sample. Method: We analyzed data from the National Health and Nutrition Examination Survey 2005-2016, using the Overactive Bladder Symptom Scale (OBSS). Logistic regression models were used to assess the association between alcohol consumption and OAB onset and severity. Results: Our analysis included 7805 samples, representing 1.47 billion Americans. About 12.4% reported OAB. OAB patients were more likely to be nondrinkers, female, older, have higher blood pressure, and lower income. Nondrinkers had a higher OAB risk than those consuming 1-10 drinks/month. The lowest quartile of alcohol consumption also had a higher risk than higher quartiles. Only those consuming >10 drinks/month had a lower risk than nondrinkers after adjustment. The second and third quartiles still showed associations. Higher appropriate alcohol consumption was linked to a lower OAB risk compared to nondrinkers and the lowest quartile. Conclusion: Our study found a significant association between alcohol consumption and OAB incidence. Long-term, alcohol may not be a risk factor for OAB. These findings suggest potential intervention targets, but need confirmation in clinical trials.

    Keywords: OAB, NHANES, Alcohol consumption, luts, Urinary Incontinence

    Received: 23 May 2024; Accepted: 06 Dec 2024.

    Copyright: © 2024 Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xinyi Zhang, Fourth military medical university, Xi'an, China

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