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ORIGINAL RESEARCH article

Front. Public Health
Sec. Public Health Education and Promotion
Volume 12 - 2024 | doi: 10.3389/fpubh.2024.1409153

Determinants of Medication Non-Adherence among Patients with Chronic Diseases at Community Pharmacy Settings in South Gondar Zone, Northwest Ethiopia: A Multicenter Cross-Sectional Study

Provisionally accepted
Tilaye Arega Moges Tilaye Arega Moges 1*Samuel Berihun Dagnew Samuel Berihun Dagnew 1Samuel A. Wondm Samuel A. Wondm 2Yared Andargie Ferede Yared Andargie Ferede 1Tesfagegn Gobezie Yiblet Tesfagegn Gobezie Yiblet 1Andargachew Almaw Andargachew Almaw 3Yohannes Shumet Yohannes Shumet 1Getu Tesfaw Addis Getu Tesfaw Addis 1Woretaw Sisay Zewdu Woretaw Sisay Zewdu 1Fisseha Nigussie Dagnew Fisseha Nigussie Dagnew 1
  • 1 Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia
  • 2 Department of Pharmacy, College of Health Science, Debre Markos University, Debre Markos, Amhara, Ethiopia
  • 3 Department of Medical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia

The final, formatted version of the article will be published soon.

    Background: Medication non-adherence is a significant public health concern in managing patients with chronic diseases, and community pharmacists are on the frontline in the management of chron ic diseases. Chronic diseases require lifelong pharmacotherapy; understanding the determinants of medication adherence is of paramount importance to develop strategies that improve medication ad herence and treatment outcomes. Thus, this study aimed to assess the magnitude of medication nonadherence and its contributing factors among patients with chronic diseases attending community pharmacies in South Gondar Zone, Northwest Ethiopia.Gondar Zone from September 01 to October 30, 2023. Medication adherence was assessed using a structured questionnaire using the Adherence in Chronic Diseases Scale (ACDS). Statistical Package for Social Sciences (SPSS) version 25 was used for analysis. Association between the outcome variable and independent variables was performed using binary logistic regression and a p-value of <0.05 was considered statistically significant.Results: From 386 study participants recruited in this study, more than half of them 222 (57.51%) at 95%CI (52.4% -62.5%) were low-adherent to their medications. Concerning determinants of medication non-adherence, the presence of side effects (AOR =2.1, 95% CI=1.33-3.29), unable to get ever counseling from community pharmacists (AOR=2.3, 95%CI= 1.46-3.58), and poor about their medications (AOR=3.1, 95% CI= 1.96-4.82) were significantly associated with patients' nonadherence to medications.Our study of medication adherence among chronic disease patients attending commu nity pharmacies found that adherence rates were suboptimal. The presence of side effects, unable to get ever counseling, and poor knowledge about their medications were statistically significant fact ors of poorer medication adherence. Hence, healthcare professionals, especially community pharm acists, have a crucial role in designing the schedule for health education concerning the needs of these patients in community pharmacy settings.

    Keywords: Medication non-adherence, Chronic Disease, determinants, Pharmacy, Patient Safety

    Received: 29 Mar 2024; Accepted: 25 Sep 2024.

    Copyright: © 2024 Moges, Dagnew, Wondm, Ferede, Yiblet, Almaw, Shumet, Tesfaw Addis, Zewdu and Dagnew. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Tilaye Arega Moges, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.