AUTHOR=Chizimu Joseph Yamweka , Mudenda Steward , Yamba Kaunda , Lukwesa Chileshe , Chanda Raphael , Nakazwe Ruth , Simunyola Bwalya , Shawa Misheck , Kalungia Aubrey Chichonyi , Chanda Duncan , Chola Uchizi , Mateele Tebuho , Thapa Jeewan , Kapolowe Kenneth , Mazaba Mazyanga Lucy , Mpundu Mirfin , Masaninga Freddie , Azam Khalid , Nakajima Chie , Suzuki Yasuhiko , Bakyaita Nathan Nsubuga , Wesangula Evelyn , Matu Martin , Chilengi Roma TITLE=Antimicrobial stewardship situation analysis in selected hospitals in Zambia: findings and implications from a national survey JOURNAL=Frontiers in Public Health VOLUME=12 YEAR=2024 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1367703 DOI=10.3389/fpubh.2024.1367703 ISSN=2296-2565 ABSTRACT=Background

Antimicrobial stewardship (AMS) programs are critical in combating antimicrobial resistance (AMR). In Zambia, there is little information regarding the capacity of hospitals to establish and implement AMS programs. The objective of this study was to conduct a baseline assessment of WHO core elements for an AMS program implementation in eight hospitals in Zambia.

Materials and methods

We conducted an exploratory cross-sectional study from September 2023 to December 2023 using a self-scoring Periodic National and Healthcare Facility Assessment Tool from the World Health Organization (WHO) policy guidance on integrated AMS activities in human health. Eight public hospitals were surveyed across the five provinces of Zambia. Data was analyzed using the WHO self-scoring tool and thematic analysis.

Results

Overall, 62.5% (6/8) of the facilities scored low (below 60%) in implementing AMS programs. Most facilities had challenges with reporting AMS feedback within the hospital (average score = 46%), Drugs and Therapeutics Committee (DTC) functionality (average score = 49%), AMS actions (average score = 50%), education and training (average score = 54%), and leadership commitment to AMS activities (average score = 56%). The overall score for all AMS core elements was average (56%). All the hospitals (100%) did not have an allocated budget for AMS programs. Finally, there were neither antibiograms to guide antimicrobial utilization nor AMS-trained staff in more than 50% of the hospitals surveyed.

Conclusion

This study found low AMS implementation in these public hospitals, especially where DTCs were non-functional. The identified challenges and gaps require urgent attention for sustainable multidisciplinary AMS programs.