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ORIGINAL RESEARCH article

Front. Public Health
Sec. Life-Course Epidemiology and Social Inequalities in Health
Volume 12 - 2024 | doi: 10.3389/fpubh.2024.1345803

A Comparative Cross-sectional Study on the Quality of Life in Grave's Disease Patients: Urban vs. Rural Perspectives

Provisionally accepted
  • 1 NIMS University, Jaipur, India
  • 2 School of Public Health, University of Alberta, Edmonton, Alberta, Canada
  • 3 School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, England, United Kingdom
  • 4 Department of Endocrinology, NIMS University, Jaipur, Rajasthan, India

The final, formatted version of the article will be published soon.

    Grave's Disease affects numerous patients globally, but its impact on health-related quality of life (HR-QoL) in relation to geographical disparities remains under-explored.This cross-sectional study aimed to assess the influence of urban versus rural residence on HR-QoL among patients diagnosed with Graves' Disease in Rajasthan, India. 107 Graves' disease patients from rural and urban endocrine centers were analyzed. The rural group included 52 patients (24 males, 28 females), averaging 38.9 ± 10.9 years of age, while the urban group had 55 (13 males, 42 females) with an average age of 39.1 ± 14.2 years. We found differences between rural and urban patients in terms of gender ratio, BMI, smoking habits, and obesity. Multivariable linear regression was used in both groups to determine the association between the baseline characteristics of Graves' patients from both areas and HR-QOL. Health-related quality of life, assessed via the SF-36 questionnaire, indicated higher general health and role emotional scores among urban patients. Our study found that the duration of Graves' disease in rural centers negatively impacted physical health scores. In urban patients, age and BMI influenced physical health, while gender and disease duration affected mental health scores in rural patients. Age impacted mental health in urban patients. Rural patients had a poorer quality of life compared to urban patients. Differences in gender distribution, BMI, smoking habits, and obesity rates revealed disparities in Graves' disease between rural and urban patients in India, highlighting the need for better healthcare infrastructure and awareness in rural areas.

    Keywords: Grave's disease, HR-QoL, Physical component summary score, Mental Component Summary score, Urban, rural

    Received: 10 Jan 2024; Accepted: 01 Aug 2024.

    Copyright: © 2024 Mishra, Singh, Rajotiya, Singh, Debnath, Raj, SINGH, Bareth, Nathiya and Singh Tomar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Dr. Sumit Rajotiya, NIMS University, Jaipur, India
    Pratima Singh, School of Public Health, University of Alberta, Edmonton, AB T6G 1C9, Alberta, Canada
    MAHAVEER SINGH, Department of Endocrinology, NIMS University, Jaipur, Rajasthan, India
    Deepak Nathiya, NIMS University, Jaipur, India

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.