AUTHOR=Skaathun Britt , Salgin Linda , Muñoz Fatima A. , Talavera Gregory A. , Smith Davey M. , Stockman Jamila K. , O’Bryan Sophie E. , Ramirez Daniel , James-Price Cynthia , Servin Argentina E. 

TITLE=Study protocol: Project 2VIDA! SARS-CoV-2 vaccine intervention delivery for adults in Southern California

JOURNAL=Frontiers in Public Health

VOLUME=12

YEAR=2024

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1291332

DOI=10.3389/fpubh.2024.1291332

ISSN=2296-2565

ABSTRACT=<sec id="sec1"><title>Background</title><p>To date, the United States (US) leads the world in the number of infections and deaths due to the Coronavirus Disease 2019 (COVID-19). Racial and ethnic disparities in COVID-19 morbidity and mortality are staggering. Age-adjusted data show that AA and Latino individuals have had higher rates of death over most of the pandemic and during surges. Project <italic>2VIDA!</italic> is community-based participatory research (CBPR) that was developed to address individual, social, and contextual factors related to access and acceptance of the COVID-19 vaccine among African American and Latino communities in Southern California. This paper describes the study protocol and overarching objectives.</p></sec><sec id="sec2"><title>Methods and design</title><p>Project <italic>2VIDA!</italic> is a multilevel intervention that builds on the principals of CBPR and is designed to increase uptake of the COVID-19 vaccine among African American and Latino individuals (≥16 years and older) in San Diego County. The intervention was developed with a working group comprised of representatives from community and academia and centers on targeted COVID-19 individual awareness and education, linkage to medical and supportive services, COVID-19 community outreach and health promotion and offering the COVID-19 vaccine through community pop-up clinics.</p></sec><sec id="sec3"><title>Discussion</title><p>Findings from <italic>2VIDA!</italic> will provide data on the impact, feasibility, and acceptability of the intervention which are all crucial for the adaptation, refinement, and improvement of vaccine outreach interventions for COVID-19 and other vaccine preventable infectious diseases that severely impact African American and Latino communities.</p></sec><sec id="sec4"><title>Clinical trial registration</title><p><ext-link xlink:href="https://clinicaltrials.gov/ct2/show/NCT05022472?term=Project+2VIDA&amp;draw=2&amp;rank=1" ext-link-type="uri" xmlns:xlink="http://www.w3.org/1999/xlink">https://clinicaltrials.gov/ct2/show/NCT05022472?term=Project+2VIDA&amp;draw=2&amp;rank=1</ext-link>, NCT05022472.</p></sec>