AUTHOR=Alberca Ricardo Wesley , Ramos Yasmim Álefe Leuzzi , Pereira Nátalli Zanete , Beserra Danielle Rosa , Branco Anna Cláudia Calvielli Castelo , Leão Orfali Raquel , Aoki Valeria , Duarte Alberto Jose da Silva , Sato Maria Notomi TITLE=Long-term effects of COVID-19 in diabetic and non-diabetic patients JOURNAL=Frontiers in Public Health VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.963834 DOI=10.3389/fpubh.2022.963834 ISSN=2296-2565 ABSTRACT=

The literature presents several reports of the impact of glycemic control and diabetes in the inflammatory and coagulatory response during coronavirus disease 2019 (COVID-19). Nevertheless, the long-term impact of the COVID-19 in diabetic patients is still to be explored. Therefore, we recruited 128 patients and performed a longitudinal analysis on COVID-19-associated biomarkers of patients with COVID-19, tree and 6 months after COVID-19 recovery and put into perspective the possible long-term complication generated after COVID-19. In our investigation, we failed to verify any long-term modification on inflammatory biomarkers, but detected an increase in the glycemia and glycated hemoglobin in patients without any pre-existing history or diagnosis of diabetes (non-diabetic patients). Although diabetic and non-diabetic patients presented elevated levels of glycated hemoglobin, the c-peptide test indicated a normal beta cell function in all patients.