AUTHOR=Zheng Chao , Yu Li-Xiang , Jia Hong-Ying , Cui Shu-De , Tian Fu-Guo , Fan Zhi-Min , Geng Cui-Zhi , Cao Xu-Chen , Yang Zhen-Lin , Wang Xiang , Liang Hong , Wang Shu , Jiang Hong-Chuan , Duan Xue-Ning , Wang Hai-Bo , Li Guo-Lou , Wang Qi-Tang , Zhang Jian-Guo , Jin Feng , Tang Jin-Hai , Li Liang , Zhu Shi-Guang , Zuo Wen-Shu , Wang Fei , Zhou Fei , Xiang Yu-Juan , Guo Ming-Ming , Wang Yong-Jiu , Huang Shu-Ya , Liu Li-Yuan , Yu Zhi-Gang 

TITLE=Relationship Between Lifestyle Habits and Health-Related Quality of Life of Recently Diagnosed Breast Cancer Patients: A Comparison Between Younger and Older Women in China

JOURNAL=Frontiers in Public Health

VOLUME=9

YEAR=2021

URL=https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2021.767151

DOI=10.3389/fpubh.2021.767151

ISSN=2296-2565

ABSTRACT=<p><bold>Objective:</bold> The aim of this study was to evaluate the relationship between lifestyle habits and health-related quality of life (HRQoL) among different ages who were initially diagnosed with breast cancer (within the first 2 weeks) and to determine the contribution of lifestyle habits factors on HRQoL.</p><p><bold>Methods:</bold> Patients with breast cancer were recruited from 22 hospitals in 11 provinces or municipalities in northern and eastern China. The Functional Assessment of Cancer Therapy-Breast Cancer (FACT-B) was used to measure HRQoL. Chi-square test, ANOVA, and multivariable generalized linear models were conducted to identify the differences in HRQoL between two age groups (age &lt;50 years and ≥50 years) and to evaluate the contribution of lifestyle habits factors on HRQoL of patients with breast cancer.</p><p><bold>Results:</bold> About 1,199 eligible patients with breast cancer were used for analysis. Younger women (aged &lt;50 years) appeared to show lower scores than older women (aged ≥50 years) in HRQoL subscales, including emotional well-being (<italic>p</italic> = 0.003), functional well-being (<italic>p</italic> = 0.006), breast cancer subscale (<italic>p</italic> = 0.038), and FACT-B Total scores (<italic>p</italic> = 0.028). Tea and alcohol consumption and being very satisfied with sleep and current life were the strongest predictors of higher HRQoL in younger group. Meanwhile, no coffee consumption, frequent participation in physical activities, high sleep satisfaction, and current life satisfaction were the key predictors of higher HRQoL in older women with breast cancer.</p><p><bold>Conclusion:</bold> The relationship of the nine lifestyle habit items with HRQoL differed among younger and older women. The associated variable of low HRQoL can help clinicians take intervention early in order to improve the prognosis of patients with breast cancer.</p>