AUTHOR=Clavijo-Moran Hugo Juan Camilo , Álvarez-García Daniela , Pinilla-Monsalve Gabriel D. , Muñoz-Ospina Beatriz , Orozco Jorge 

TITLE=Psychometric properties and construct validity of the Parkinson’s Disease-Cognitive Rating Scale (PD-CRS) in Colombia

JOURNAL=Frontiers in Psychology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2022.1018176

DOI=10.3389/fpsyg.2022.1018176

ISSN=1664-1078

ABSTRACT=<sec><title>Background</title><p>Cognitive impairment is frequent among people living with Parkinson’s disease: up to 40% of patients exhibit symptoms of mild cognitive impairment and 25% meet the criteria for dementia. Parkinson’s Disease Cognitive Rating Scale (PD-CRS) is one of the recommended scales by the Movement Disorders Society Task Force for level 1 screening of dementia. However, its psychometric properties have not been studied in the Colombian population.</p></sec><sec><title>Methods</title><p>A cross-sectional study was conducted on 100 patients with Parkinson’s disease diagnosed by a movement disorders neurologist. Patients were evaluated with PD-CRS and MoCA. Principal component analysis was conducted, and then confirmatory factor analysis was implemented through the maximum-likelihood method. Internal consistency was evaluated using Cronbach <italic>α</italic>. Convergent and divergent validity were also calculated and concurrent validity with the MoCA was assessed.</p></sec><sec><title>Results</title><p>62% were males. Their median age was 68 years (IQR 57–74) and the median disease duration was 4 years (IQR 2–9). 77% were classified in early stages (Hoehn and Yahr stage ≤ 2), while the MDS-UPDRS part III score was 25 (IQR 15.5–38). In the principal component factor analysis, the pattern matrix unveiled a mnesic and a non-mnesic domain. Confirmatory factor analysis showed similar explanatory capacity (<italic>λ</italic> ≥ 0.50) for items other than naming (<italic>λ</italic> = 0.34). Cronbach’s <italic>α</italic> for the full 9-items instrument was 0.74. MoCA and PD-CRS total scores were correlated (<italic>ρ</italic> = 0.71, <italic>p</italic> = 0.000). Assuming a cut-off score of 62 points, there is an agreement of 89% with the definition of dementia by MoCA for Colombia (<italic>κ</italic> = 0.59; <italic>p</italic> = 0.000).</p></sec><sec><title>Conclusion</title><p>PD-CRS has acceptable psychometric properties for the Colombian population and has significant correlation and agreement with a validated scale (MoCA).</p></sec>