AUTHOR=Mokhtar Norfilza Mohd , Bahrudin Mohd Fyzal , Abd Ghani Nazierah , Abdul Rani Rafiz , Raja Ali Raja Affendi TITLE=Prevalence of Subthreshold Depression Among Constipation-Predominant Irritable Bowel Syndrome Patients JOURNAL=Frontiers in Psychology VOLUME=11 YEAR=2020 URL=https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2020.01936 DOI=10.3389/fpsyg.2020.01936 ISSN=1664-1078 ABSTRACT=
Patients suffering from irritable bowel syndrome (IBS) may have some form of affective disorders that may worsen their symptoms. Lack of screening among IBS patients is one of the reasons for depression unawareness among healthcare providers. The present study was conducted to evaluate the prevalence of depression among patients with constipation-predominant IBS (IBS-C). A total of 240 IBS patients who fulfilled Rome III criteria were enrolled. The psychiatric assessment was evaluated using the Center for Epidemiologic Studies Depression Scale Revised (CESD-R). Twenty items in CESD-R scale measured symptoms of depression in nine separate groups. Patients were categorized into five different subgroups: major depressive episode, probable major depressive episode, possible major depressive episode, subthreshold depressive symptoms, and without clinical significance of depression. Out of the 240 patients with IBS-C, the majority (