AUTHOR=Kadipasaoglu Cihan M., Forseth Kiefer , Whaley Meagan , Conner Christopher R., Rollo Matthew J., Baboyan Vatche G., Tandon Nitin 

TITLE=Development of grouped icEEG for the study of cognitive processing

JOURNAL=Frontiers in Psychology

VOLUME=6

YEAR=2015

URL=https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2015.01008

DOI=10.3389/fpsyg.2015.01008

ISSN=1664-1078

ABSTRACT=<p>Invasive intracranial EEG (icEEG) offers a unique opportunity to study human cognitive networks at an unmatched spatiotemporal resolution. To date, the contributions of icEEG have been limited to the individual-level analyses or cohorts whose data are not integrated in any way. Here we discuss how grouped approaches to icEEG overcome challenges related to sparse-sampling, correct for individual variations in response and provide statistically valid models of brain activity in a population. By the generation of whole-brain activity maps, grouped icEEG enables the study of intra and interregional dynamics between distributed cortical substrates exhibiting task-dependent activity. In this fashion, grouped icEEG analyses can provide significant advances in understanding the mechanisms by which cortical networks give rise to cognitive functions.</p>