94% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
STUDY PROTOCOL article
Front. Psychiatry
Sec. Mood Disorders
Volume 16 - 2025 | doi: 10.3389/fpsyt.2025.1584306
Efficacy of Chinese Herbal Medicine in the treatment of anxiety and depression in male sexual dysfunction: A Systematic Review and Meta-Analysis Protocol
Provisionally accepted- 1Shandong University of Traditional Chinese Medicine, Jinan, China
- 2China-Japan Friendship Hospital, Beijing, Beijing Municipality, China
- 3Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Background: Male Sexual Dysfunction (MSD), comprising erectile dysfunction (ED), premature ejaculation, and hypoactive sexual desire disorder, exhibits an age-related prevalence affecting 50% of males beyond their fourth decade. Epidemiological studies demonstrate ED prevalence rates of 79.4% in general clinical populations. Beyond physiological manifestations, MSD with comorbid anxiety and depression exerts profound psychosocial impacts, potentially exacerbating pre-existing mental health conditions and impairing interpersonal relationships. Emerging evidence suggests Chinese Herbal Medicine (CHM) may offer therapeutic potential for addressing this clinical intersection. Therefore, this study will perform a systematic review and meta-analysis to assess the efficacy of various CHM interventions for MSD patients with comorbid anxiety and depression.
Keywords: This study will systematically search four Chinese databases (China National Male Sexual Dysfunction, Herbal Chinese Medicine, Anxiety, Depression, Systematic review, psychosexual health
Received: 03 Mar 2025; Accepted: 09 Apr 2025.
Copyright: © 2025 Xie, Zhang, Jia and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Hongling Jia, Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, China
Yongchen Zhang, Shandong University of Traditional Chinese Medicine, Jinan, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.