
94% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
BRIEF RESEARCH REPORT article
Front. Psychiatry
Sec. Addictive Disorders
Volume 16 - 2025 | doi: 10.3389/fpsyt.2025.1544435
The final, formatted version of the article will be published soon.
You have multiple emails registered with Frontiers:
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Individuals with comorbid posttraumatic stress disorder (PTSD) and substance use disorder (SUD) present with a diversity of symptoms. Current interventions show minimal efficacy differences and have high attrition. Offering a variety of treatment options, including virtual ones, ensures treatment access that is appropriate and acceptable to individual needs. We conducted a single-arm pilot study to examine the acceptability and feasibility of an online intervention based on Internal Family Systems (IFS), called the Program for Alleviating and Reducing Trauma, Stress, and Substance Use (PARTS-SUD). Ten adults (N=10), with comorbid diagnoses of PTSD and SUD, were allocated to 12 weekly groups with 6 individual counseling sessions. Our pre-specified aims were acceptability (70% overall acceptability, 75% willingness to refer a friend), and feasibility (70% completion), with key exploratory clinical outcomes (PTSD symptom severity and craving). Participants rated the intervention with a mean score of 86% on acceptability, 92% on willingness to refer a friend, retaining 70% of participants at 12 weeks. Furthermore, PTSD symptoms reduced by 1.7 points/week (95% CI: -2.45, -0.93, p=0.002) with 54% of the sample achieving a minimally important difference in PCL-5 scores. Craving Scale scores were reduced by 0.25 points/week (95% CI: -0.45, -0.06, p=0.014). An online IFS intervention was a feasible and acceptable way to provide whole-person treatment for people with PTSD-SUD within a diverse community mental health center setting. Despite being a small pilot study, decreases in both PTSD symptom severity and craving indicate the need for a randomized controlled trial with a large, diverse sample.
Keywords: PTSD-SUD, Addiction, Trauma, Internal family systems, telehealth, whole-person treatment, community mental health
Received: 12 Dec 2024; Accepted: 03 Mar 2025.
Copyright: © 2025 Ally, Tobiasz-Veltz, Tu, Comeau, Bumpus, Blot, Rice, Orr, Soumerai Rea, Sweezy and Schuman-Olivier. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Zev Schuman-Olivier, Harvard Medical School, Boston, United States
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Research integrity at Frontiers
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.